Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 14/20 | 0.73 |
| ▸ | CA12 | O43570 | 7/20 | 0.66 |
| ▸ | CA1 | P00915 | 7/20 | 0.66 |
| ▸ | CA2 | P00918 | 7/20 | 0.66 |
| ▸ | CA6 | P23280 | 7/20 | 0.66 |
| ▸ | CA7 | P43166 | 7/20 | 0.66 |
| ▸ | CA9 | Q16790 | 7/20 | 0.66 |
| ▸ | CA14 | Q9ULX7 | 7/20 | 0.66 |
| ▸ | CA5B | Q9Y2D0 | 7/20 | 0.66 |
| ▸ | CA5A | P35218 | 6/20 | 0.66 |
| ▸ | CA4 | P22748 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | HTR1A | P08908 | 1/20 | 0.66 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.66 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.66 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.66 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.66 |
| ▸ | CA3 | P07451 | 6/20 | 0.59 |
| ▸ | CA13 | Q8N1Q1 | 6/20 | 0.59 |
| ▸ | APP | P05067 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11823275 | 0.89 | CISD1 (0.57) | CISD1CA12CA1CA2CA6 | |
| SCHEMBL11818526 | 0.86 | CISD1 (0.62) | CISD1CA12CA1CA2CA6 | |
| SCHEMBL1716052 | 0.84 | CISD1 (1.00) | CISD1CA12CA1CA2CA6 | |
| SCHEMBL11790756 | 0.83 | CISD1 (0.58) | CISD1CA12CA1CA2CA6 | |
| SCHEMBL11778816 | 0.81 | CISD1 (0.48) | CISD1CA12CA1CA2CA6 | |
| SCHEMBL11788087 | 0.81 | CISD1 (0.53) | CISD1CA12CA1CA2CA6 | |
| Aniline SCHEMBL11799081 | 0.81 | CISD1 (0.53) | CISD1CA12CA1CA2CA6 | |
| SCHEMBL11788824 | 0.81 | CISD1 (0.53) | CISD1CA12CA1CA2CA6 | |
| Furosemide SCHEMBL29406913 | 0.80 | CISD1 (1.00) | CISD1CA12CA1CA2CA6 | |
| Furosemide SCHEMBL428921 | 0.80 | CISD1 (1.00) | CISD1CA12CA1CA2CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220184008-A1 | MODULATORS OF INTRACELLULAR CHLORIDE CONCENTRATION | ALMA MATER STUDIORUM - UNIVERSITA' DI BOLOGNA (IT) | 2022-06-16 | — | — | US | disclosed |
| WO-2020202072-A1 | MODULATORS OF INTRACELLULAR CHLORIDE CONCENTRATION | FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA (IT) | 2020-10-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220184008-A1 | MODULATORS OF INTRACELLULAR CHLORIDE CONCENTRATION | SLC6A1, SLC6A13, SLC6A11 | CISD1 1949/4885CA12 2754/4885CA1 667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.