SCHEMBL11778697

SCHEMBL11778697

CCOCCOC(=O)Nc1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 4/20 0.64
RAB9A P51151 4/20 0.64
SMN1; SMN2 Q16637 3/20 0.64
TSHR P16473 1/20 0.64
RECQL P46063 1/20 0.62
LMNA P02545 3/20 0.60
MEN1 O00255 2/20 0.60
KMT2A Q03164 2/20 0.60
NPSR1 Q6W5P4 2/20 0.60
TP53 P04637 1/20 0.60
HPGD P15428 2/20 0.56
CRHBP P24387 1/20 0.56
CRHR2 Q13324 1/20 0.56
MAPT P10636 1/20 0.55
MAPK1 P28482 1/20 0.55
HSD17B10 Q99714 1/20 0.55
MGLL Q99685 1/20 0.51
ALDH1A1 P00352 1/20 0.51
CHRNA7 P36544 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26103539 0.98 NPC1 (0.62) NPC1RAB9ASMN1; SMN2TSHRRECQL
SCHEMBL10596423 0.90 NPC1 (0.72) NPC1RAB9ASMN1; SMN2TSHRRECQL
SCHEMBL17346621 0.90 NPC1 (0.72) NPC1RAB9ASMN1; SMN2TSHRRECQL
Ethyl Phenylcarbamate SCHEMBL10645992 0.86 RAB9A (0.69) NPC1RAB9ASMN1; SMN2TSHRRECQL
SCHEMBL1844334 0.86 RAB9A (0.61) NPC1RAB9ASMN1; SMN2TSHRRECQL
SCHEMBL12407197 0.85 SMN1; SMN2 (0.57) NPC1RAB9ASMN1; SMN2RECQLLMNA
SCHEMBL3229905 0.84 HPGD (0.67) NPC1RAB9ASMN1; SMN2TSHRRECQL
Ethyl Phenylcarbamate SCHEMBL264865 0.84 RAB9A (0.75) NPC1RAB9ASMN1; SMN2TSHRRECQL
Ethyl Phenylcarbamate SCHEMBL11593824 0.84 RAB9A (0.75) NPC1RAB9ASMN1; SMN2TSHRRECQL
SCHEMBL5623097 0.83 NPC1 (0.68) NPC1RAB9ASMN1; SMN2TSHRRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4665710-A1 METHOD FOR CLEAVING URETHANES Covestro Deutschland AG (DE) 2025-12-24 EP disclosed
EP-4665711-A1 METHOD FOR CLEAVING (POLY)URETHANES Covestro Deutschland AG (DE) 2025-12-24 EP disclosed
WO-2024170559-A1 METHOD FOR CLEAVING (POLY)URETHANES COVESTRO DEUTSCHLAND AG (DE) 2024-08-22 WO disclosed
WO-2024170558-A1 METHOD FOR CLEAVING URETHANES COVESTRO DEUTSCHLAND AG (DE) 2024-08-22 WO disclosed
US-3971741-A DISPERSION PIGMENTS BAYER AKTIENGESELLSCHAFT (DT) 1976-07-27 US disclosed