Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.66 |
| ▸ | RAB9A | P51151 | 5/20 | 0.65 |
| ▸ | NPC1 | O15118 | 4/20 | 0.65 |
| ▸ | TSHR | P16473 | 1/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.63 |
| ▸ | RECQL | P46063 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.60 |
| ▸ | TP53 | P04637 | 2/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | CRHBP | P24387 | 1/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7562459 | 0.90 | SMN1; SMN2 (0.77) | HPGDSMN1; SMN2ALDH1A1MAPK1RAB9A | |
| SCHEMBL3765824 | 0.89 | RAB9A (0.69) | HPGDSMN1; SMN2ALDH1A1MAPK1RAB9A | |
| SCHEMBL8600999 | 0.88 | RAB9A (0.67) | HPGDSMN1; SMN2ALDH1A1MAPK1RAB9A | |
| SCHEMBL7564873 | 0.87 | HPGD (0.79) | HPGDSMN1; SMN2ALDH1A1MAPK1RAB9A | |
| SCHEMBL7562461 | 0.87 | SMN1; SMN2 (0.69) | HPGDSMN1; SMN2ALDH1A1MAPK1RAB9A | |
| SCHEMBL8600460 | 0.86 | RAB9A (0.65) | HPGDSMN1; SMN2ALDH1A1MAPK1RAB9A | |
| SCHEMBL1834100 | 0.86 | RAB9A (0.65) | HPGDSMN1; SMN2ALDH1A1MAPK1RAB9A | |
| SCHEMBL8076542 | 0.86 | RAB9A (0.65) | HPGDSMN1; SMN2ALDH1A1MAPK1RAB9A | |
| SCHEMBL1837292 | 0.86 | RAB9A (0.65) | HPGDSMN1; SMN2ALDH1A1MAPK1RAB9A | |
| SCHEMBL10599124 | 0.86 | RAB9A (0.65) | HPGDSMN1; SMN2ALDH1A1MAPK1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113024418-B | Method for synthesizing alicyclic carbamate by using isopropanol as hydrogen source | 河北工业大学 | 2023-01-24 | — | — | CN | claimed |
| CN-112898184-A | Method for continuously synthesizing alicyclic carbamate | 河北工业大学 | 2021-06-04 | — | — | CN | claimed |
| US-5079383-A | With A Methylating Agent Using A Zinc Halide Catalyst | MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) | 1992-01-07 | — | — | US | claimed |
| EP-0450039-A1 | DIHYDRO-1,2 OXO-2 QUINOXALINE DERIVATES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPEUTICS. | FABRE PIERRE COSMETIQUE (FR) | 1991-10-09 | — | — | EP | claimed |
| JP-3167104-A | — | — | None | — | — | JP | disclosed |
| US-20240425448-A1 | METHOD FOR PRODUCING ISOCYANATE COMPOUND, METHOD FOR PRODUCING CARBAMATE COMPOUND, METHOD FOR RECOVERING AMINE COMPOUND, AND ISOCYANATE COMPOSITION | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2024-12-26 | — | — | US | disclosed |
| EP-4431490-A1 | METHOD FOR PRODUCING ISOCYANATE COMPOUNDS, METHOD FOR PRODUCING CARBAMATE COMPOUNDS, METHOD FOR RECOVERING AMINE COMPOUNDS, AND ISOCYANATE COMPOSITION | Asahi Kasei Kabushiki Kaisha (JP) | 2024-09-18 | — | — | EP | disclosed |
| CN-118215651-A | Method for producing isocyanate compound, method for producing urethane compound, method for recovering amine compound, and isocyanate composition | 旭化成株式会社 | 2024-06-18 | — | — | CN | disclosed |
| WO-2023080257-A1 | METHOD FOR PRODUCING ISOCYANATE COMPOUNDS, METHOD FOR PRODUCING CARBAMATE COMPOUNDS, METHOD FOR RECOVERING AMINE COMPOUNDS, AND ISOCYANATE COMPOSITION | 旭化成株式会社 | 2023-05-11 | — | — | WO | disclosed |
| CN-112020493-B | Method for producing urethane and method for producing isocyanate | 旭化成株式会社 | 2023-04-21 | — | — | CN | disclosed |
| EP-4161902-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. (US) | 2023-04-12 | — | — | EP | disclosed |
| CN-113024418-B | Method for synthesizing alicyclic carbamate by using isopropanol as hydrogen source | 河北工业大学 | 2023-01-24 | — | — | CN | disclosed |
| US-4552974-A | Process for producing diphenylmethane dicarbamates | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1985-11-12 | — | — | US | disclosed |
| US-4547322-A | Method for manufacture of diphenylmethane diisocyanates | ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) | 1985-10-15 | — | — | US | disclosed |
| US-4487713-A | HEAT TREATMENT WITH TITANIUM, TIN, ANTIMONY OR ZIRCONIUM COMPOUND | EXXON RESEARCH & ENGINEERING CO. (US) | 1984-12-11 | — | — | US | disclosed |
| EP-0123412-A1 | Method for manufacture of diphenylmethane diisocyanates | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1984-10-31 | — | — | EP | disclosed |
| EP-0110732-A2 | Process for producing diphenylmethane dicarbamates | Asahi Kasei Kogyo Kabushiki Kaisha (JP) | 1984-06-13 | — | — | EP | disclosed |
| US-4328354-A | Preparation of methylene-bis-phenylcarbamic acid esters and polymethylene-polyphenylcarbamic acid esters | BASF AKTIENGESELLSCHAFT (DE) | 1982-05-04 | — | — | US | disclosed |
| US-4081472-A | CATALYTIC, FROM A CARBAMATE | MITSUI TOATSU CHEMICALS INC. (JA) | 1978-03-28 | — | — | US | disclosed |
| US-3938986-A | ISOPROPYL N-PHENYLCARBAMATE OR ISOPROPYL N-(3-CHLOROPHENYL)CARBAMATE AND 4-CHLOROPHENYL N-METHYLCARBAMATE | PPG INDUSTRIES, INC. (US) | 1976-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240425448-A1 | METHOD FOR PRODUCING ISOCYANATE COMPOUND, METHOD FOR PRODUCING CARBAMATE COMPOUND, METHOD FOR RECOVERING AMINE COMPOUND, AND ISOCYANATE COMPOSITION | IDH3A, CA7, C9 | HPGD 775/4885SMN1; SMN2 2354/4885ALDH1A1 630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.