Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.59 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PTGES | O14684 | 3/20 | 0.48 |
| ▸ | TOP2A | P11388 | 1/20 | 0.48 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.45 |
| ▸ | PTPN11 | Q06124 | 4/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 3/20 | 0.42 |
| ▸ | CA7 | P43166 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11776746 | 0.86 | CYP3A4 (0.49) | NR1H2NR1H3CYP3A4TDP1SMN1; SMN2 | |
| SCHEMBL29979434 | 0.83 | PTGES (0.66) | NR1H2NR1H3CYP3A4TDP1SMN1; SMN2 | |
| SCHEMBL8750720 | 0.83 | PTGES (0.66) | NR1H2NR1H3CYP3A4TDP1SMN1; SMN2 | |
| SCHEMBL8400549 | 0.82 | PTPN1 (0.66) | NR1H2NR1H3CYP3A4TDP1SMN1; SMN2 | |
| SCHEMBL8402307 | 0.82 | PTPN1 (0.66) | NR1H2NR1H3CYP3A4TDP1SMN1; SMN2 | |
| SCHEMBL19409973 | 0.82 | NR1H2 (0.72) | NR1H2NR1H3CYP3A4TDP1SMN1; SMN2 | |
| SCHEMBL29647790 | 0.80 | PTPN1 (0.59) | CYP3A4PTGESTOP2APTPN1PTPN11 | |
| SCHEMBL11777217 | 0.80 | PTGES (0.42) | NR1H2NR1H3PTGESTOP2APTPN1 | |
| SCHEMBL24565087 | 0.77 | NR1H2 (0.70) | NR1H2NR1H3CYP3A4TDP1SMN1; SMN2 | |
| SCHEMBL29266100 | 0.77 | NR1H2 (0.59) | NR1H2NR1H3CYP3A4TDP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3957825-A | PROCESS FOR SYNTHESIZING ZEARALANONE AND RELATED COMPOUNDS | COMMERCIAL SOLVENTS CORPORATION (US) | 1976-05-18 | — | — | US | claimed |
| US-3957825-A | PROCESS FOR SYNTHESIZING ZEARALANONE AND RELATED COMPOUNDS | COMMERCIAL SOLVENTS CORPORATION (US) | 1976-05-18 | — | — | US | disclosed |
| US-3957825-A | PROCESS FOR SYNTHESIZING ZEARALANONE AND RELATED COMPOUNDS | COMMERCIAL SOLVENTS CORPORATION (US) | 1976-05-18 | — | — | US | disclosed |