SCHEMBL11779484

SCHEMBL11779484

CCCN(Cl)S(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSEN1 P49768 2/20 0.48
PSEN2 P49810 2/20 0.48
APH1B Q8WW43 2/20 0.48
NCSTN Q92542 2/20 0.48
APH1A Q96BI3 2/20 0.48
PSENEN Q9NZ42 2/20 0.48
CNR2 P34972 4/20 0.47
MAPT P10636 1/20 0.47
MCOLN3 Q8TDD5 1/20 0.47
GLA P06280 1/20 0.46
MCHR1 Q99705 1/20 0.45
MEN1 O00255 2/20 0.45
KMT2A Q03164 2/20 0.45
C5AR1 P21730 2/20 0.44
AGER Q15109 1/20 0.44
CYP2C8 P10632 1/20 0.44
CYP2C9 P11712 1/20 0.44
CYP2C18 P33260 1/20 0.44
CYP2C19 P33261 1/20 0.44
ATM Q13315 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27865735 0.89 MEN1 (0.51) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL9510936 0.85 MAPT (0.50) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL11170690 0.83 TDP1 (0.58) MEN1KMT2ACYP2C19CA12CA9
Ditolamide SCHEMBL2110790 0.81 CA9 (0.64) CNR2GLAMEN1KMT2ACA12
SCHEMBL11705623 0.80 MAPT (0.46) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL10282765 0.79 MAPT (0.53) PSEN1PSEN2APH1BNCSTNAPH1A
SCHEMBL1181090 0.79 C5AR1 (0.60) CNR2MAPTMCOLN3GLAC5AR1
SCHEMBL1738729 0.78 AGER (0.49) PSEN1PSEN2APH1BNCSTNAPH1A
Water SCHEMBL11781089 0.77 GLA (0.43) CNR2MAPTMCOLN3GLAMCHR1
SCHEMBL29144994 0.76 MAPT (0.46) PSEN1PSEN2APH1BNCSTNAPH1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3960744-A BLUING DYE PRECURSOR, BUILDER KAO SOAP CO., LTD. (JA) 1976-06-01 US disclosed