Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.50 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.50 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.50 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.50 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.50 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.50 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CNR2 | P34972 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11779484 | 0.89 | PSEN1 (0.48) | MEN1KMT2AATMPSEN1PSEN2 | |
| SCHEMBL6688621 | 0.84 | TDP1 (0.69) | MEN1KMT2AATMTDP1CNR2 | |
| SCHEMBL3694171 | 0.82 | CNR2 (0.58) | MEN1KMT2APSEN1PSEN2APH1B | |
| SCHEMBL9510936 | 0.82 | MAPT (0.50) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| Water SCHEMBL11781089 | 0.81 | GLA (0.43) | MEN1KMT2AATMMCHR1TDP1 | |
| SCHEMBL12169294 | 0.81 | LMNA (0.52) | MEN1KMT2AATMPSEN1PSEN2 | |
| SCHEMBL2469274 | 0.79 | KDM4E (0.59) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL14229013 | 0.79 | CA9 (0.61) | MEN1KMT2APSEN1PSEN2APH1B | |
| SCHEMBL11707759 | 0.78 | MCHR1 (0.49) | MEN1KMT2AATMPSEN1PSEN2 | |
| SCHEMBL11751198 | 0.78 | MCHR1 (0.49) | MEN1KMT2AATMPSEN1PSEN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102617512-B | Method for preparation of tetrahydropyrrole | UNIV WUHAN | 2013-11-13 | — | — | CN | disclosed |
| CN-102617512-A | Method for preparation of tetrahydropyrrole | UNIV WUHAN | 2012-08-01 | — | — | CN | disclosed |