Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.62 |
| ▸ | ACE | P12821 | 13/20 | 0.56 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11776958 | 0.94 | CTSL (0.61) | CTSLACEITGB3ITGA2BACE2 | |
| SCHEMBL11779119 | 0.93 | CTSL (0.60) | CTSLACEITGB3ITGA2BACE2 | |
| SCHEMBL11779914 | 0.87 | CTSL (0.68) | CTSLITGB3ITGA2BPARP10MEN1 | |
| SCHEMBL10802837 | 0.84 | CTSL (0.71) | CTSLACEITGB3ITGA2BMEN1 | |
| SCHEMBL11746806 | 0.84 | CTSL (0.71) | CTSLACEITGB3ITGA2BMEN1 | |
| SCHEMBL11781869 | 0.84 | CTSL (0.48) | CTSLACEITGB3ITGA2BMEN1 | |
| SCHEMBL11776346 | 0.84 | CTSL (0.51) | CTSLACEITGB3ITGA2BMEN1 | |
| SCHEMBL11781767 | 0.83 | CTSL (0.50) | CTSLACEITGB3ITGA2BMEN1 | |
| SCHEMBL11777520 | 0.81 | CTSL (0.73) | CTSLITGB3ITGA2BMEN1KMT2A | |
| SCHEMBL11121940 | 0.78 | ACE (0.59) | CTSLACEITGB3ITGA2BGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4004008-A | ANTISPASMODIC, VASODILATION | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1977-01-18 | — | — | US | disclosed |