Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 7/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 7/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 7/20 | 0.47 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11776346 | 0.89 | CTSL (0.51) | CTSLCA2PRSS1TMPRSS15KMT2A | |
| SCHEMBL11776958 | 0.89 | CTSL (0.61) | CTSLTMPRSS15KMT2AMEN1ITGB3 | |
| SCHEMBL11781767 | 0.86 | CTSL (0.50) | CTSLCA2PRSS1TMPRSS15KMT2A | |
| SCHEMBL11779119 | 0.86 | CTSL (0.60) | CTSLPRSS1PRSS2PRSS3TMPRSS15 | |
| SCHEMBL11778432 | 0.85 | CA2 (0.52) | CTSLCA2SMN1; SMN2MAPTITGB3 | |
| SCHEMBL11779923 | 0.84 | CTSL (0.62) | CTSLKMT2AMEN1ITGB3ITGA2B | |
| SCHEMBL11744597 | 0.83 | CA2 (0.63) | CTSLCA2PRSS1PRSS2PRSS3 | |
| SCHEMBL11779573 | 0.81 | CHRM2 (0.54) | CA2PTPN1ITGB3ITGA2BGAA | |
| SCHEMBL11779914 | 0.75 | CTSL (0.68) | CTSLCA2PRSS1TMPRSS15PTPN1 | |
| SCHEMBL11777532 | 0.73 | KMT2A (0.46) | CTSLCA2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4004008-A | ANTISPASMODIC, VASODILATION | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1977-01-18 | — | — | US | disclosed |