SCHEMBL11780486

SCHEMBL11780486

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nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Water SCHEMBL28770543 0.84 TSHR (0.31) ALDH1A1TSHR
Water SCHEMBL28143046 0.84 TSHR (0.31) ALDH1A1TSHR
Thiocyanic Acid SCHEMBL757271 0.82 CA1 (0.35) ALDH1A1TSHR
Thiocyanic Acid SCHEMBL757270 0.82 ALDH1A1 (0.33) ALDH1A1TSHR
SCHEMBL11780479 0.82 ALDH1A1 (0.33) ALDH1A1TSHR
Cyanate SCHEMBL1073067 0.82 CA1 (0.35) ALDH1A1TSHR
Cyanate SCHEMBL1073063 0.82 ALDH1A1 (0.33) ALDH1A1TSHR
Water SCHEMBL27550759 0.81
SCHEMBL197824 0.80 TSHR (0.33) ALDH1A1TSHR
Hydrogen Sulfide SCHEMBL28090943 0.80 TSHR (0.33) ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4009328-A Aminoglycoside 66-40C, method for its manufacture, method for its use as an intermediate in the preparation of known antibiotics and novel antibacterials SCHERING CORPORATION (US) 1977-02-22 US claimed