Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.50 |
| ▸ | MERTK | Q12866 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10817393 | 0.91 | ALDH1A1 (0.56) | TDP1MERTKALDH1A1HTTLMNA | |
| SCHEMBL31009380 | 0.88 | PDE7A (0.57) | TDP1PDE7AMERTKALDH1A1HTT | |
| SCHEMBL16792372 | 0.86 | ALDH1A1 (0.57) | TDP1MERTKALDH1A1HTTLMNA | |
| Chlomethoxyfen SCHEMBL8538106 | 0.86 | TDP1 (0.68) | TDP1PDE7AALDH1A1HTTLMNA | |
| Chlomethoxyfen SCHEMBL38653 | 0.86 | TDP1 (0.68) | TDP1PDE7AALDH1A1HTTLMNA | |
| SCHEMBL4229158 | 0.85 | ALDH1A1 (0.55) | TDP1PDE7AMERTKALDH1A1HTT | |
| SCHEMBL11781925 | 0.84 | TDP1 (0.50) | TDP1PDE7AMERTKALDH1A1HTT | |
| SCHEMBL102625 | 0.84 | TSHR (0.58) | TDP1PDE7AALDH1A1LMNAL3MBTL1 | |
| SCHEMBL7005240 | 0.84 | ALDH1A1 (0.47) | TDP1MERTKALDH1A1HTTLMNA | |
| SCHEMBL1298266 | 0.83 | MERTK (0.52) | TDP1MERTKALDH1A1HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6316386-B1 | HERBICIDES AND ANTIGROWTH AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2001-11-13 | — | — | US | disclosed |
| US-4339462-A | BACTERICIDES | CIBA-GEIGY CORPORATION (US) | 1982-07-13 | — | — | US | disclosed |
| US-4268693-A | 3-Hydroxydiphenyl ethers | CIBA-GEIGY CORPORATION (US) | 1981-05-19 | — | — | US | disclosed |