Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 8/20 | 0.58 |
| ▸ | TDO2 | P48775 | 8/20 | 0.58 |
| ▸ | IDO2 | Q6ZQW0 | 3/20 | 0.58 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | ACAT1 | P24752 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11778315 | 0.81 | IDO1 (0.53) | IDO1TDO2IDO2TSHRHIF1A | |
| SCHEMBL9771546 | 0.79 | IDO1 (0.50) | IDO1TDO2IDO2TSHRHIF1A | |
| SCHEMBL11777166 | 0.79 | IDO1 (0.55) | IDO1TDO2IDO2TSHRCYP2C9 | |
| SCHEMBL5009566 | 0.79 | TSHR (0.44) | IDO1TDO2IDO2TSHRHIF1A | |
| SCHEMBL31409210 | 0.79 | TSHR (0.44) | IDO1TDO2IDO2TSHRHIF1A | |
| SCHEMBL3924304 | 0.76 | IDO1 (0.47) | IDO1TDO2IDO2TSHRCYP2C9 | |
| SCHEMBL11780210 | 0.74 | IDO1 (0.52) | IDO1TDO2IDO2TSHRHIF1A | |
| SCHEMBL11778678 | 0.74 | IDO1 (0.56) | IDO1TDO2TSHRHIF1ALMNA | |
| SCHEMBL11376301 | 0.69 | ALDH1A1 (0.45) | IDO1TDO2IDO2LMNAMAPT | |
| SCHEMBL11092514 | 0.68 | CYP3A4 (0.50) | IDO1TDO2IDO2CYP2C9LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3956264-A | Basic azo dyestuffs having indolyl-methyleneamino substituent in the diazo component | BAYER AKTIENGESELLSCHAFT (DT) | 1976-05-11 | — | — | US | disclosed |