SCHEMBL31409210

SCHEMBL31409210

Nc1ccc(C(c2ccc(N)cc2)c2ccccc2Cl)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.44
IDO1 P14902 3/20 0.44
TDO2 P48775 3/20 0.44
HIF1A Q16665 2/20 0.44
IDO2 Q6ZQW0 2/20 0.44
LMNA P02545 2/20 0.44
MAPT P10636 2/20 0.44
CYP3A4 P08684 2/20 0.44
CYP2C19 P33261 2/20 0.44
CYP2C9 P11712 1/20 0.44
KDM4E B2RXH2 1/20 0.44
NR1I2 O75469 1/20 0.44
ABCB11 O95342 1/20 0.44
NR3C1 P04150 1/20 0.44
PGR P06401 1/20 0.44
ADRA2A P08913 1/20 0.44
ADORA3 P0DMS8 1/20 0.44
CNR1 P21554 1/20 0.44
SLC6A2 P23975 1/20 0.44
ACAT1 P24752 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5009566 1.00 TSHR (0.44) TSHRIDO1TDO2HIF1AIDO2
2-Chlorophenyl-Bisphenylmethane(Major) SCHEMBL41575 0.82 IDO1 (0.55) TSHRIDO1TDO2HIF1AIDO2
2-Chlorophenyl-Bisphenylmethane(Major) SCHEMBL29279416 0.80 IDO1 (0.57) TSHRIDO1TDO2HIF1AIDO2
SCHEMBL5009560 0.80 ADRB2 (0.52) TSHRIDO1TDO2HIF1AIDO2
SCHEMBL5009561 0.80 MAOB (0.53) TSHRIDO1TDO2HIF1AIDO2
SCHEMBL7917310 0.79 ALDH1A1 (0.55) TSHRIDO1TDO2HIF1AIDO2
SCHEMBL5010101 0.79 TSHR (0.45) TSHRIDO1TDO2HIF1AIDO2
SCHEMBL11782814 0.79 IDO1 (0.58) TSHRIDO1TDO2HIF1AIDO2
SCHEMBL30602819 0.78 CYP3A4 (0.39) TSHRMAPTCYP3A4CYP2C19CYP2C9
SCHEMBL5011789 0.77 CYP3A4 (0.39) TSHRLMNAMAPTCYP3A4SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119219504-B Method for synthesizing triarylmethane molecular skeleton by aromatic aldehyde and hydrazine hydrochloride substance 山东金科力电源科技有限公司 2025-03-14 CN claimed
CN-119219504-A Method for synthesizing triarylmethane molecular skeleton by aromatic aldehyde and hydrazine hydrochloride substance 山东金科力电源科技有限公司 2024-12-31 CN claimed
CN-119219504-B Method for synthesizing triarylmethane molecular skeleton by aromatic aldehyde and hydrazine hydrochloride substance 山东金科力电源科技有限公司 2025-03-14 CN disclosed
CN-119219504-A Method for synthesizing triarylmethane molecular skeleton by aromatic aldehyde and hydrazine hydrochloride substance 山东金科力电源科技有限公司 2024-12-31 CN disclosed