Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | CES1 | P23141 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11782830 | 0.70 | HPGD (0.43) | HPGDKMT2AMEN1TSHRMAPK1 | |
| SCHEMBL1592873 | 0.65 | NISCH (0.47) | HPGDNISCHKMT2AMEN1TSHR | |
| SCHEMBL104727 | 0.65 | IRAK4 (0.48) | HPGDNISCHKMT2AMEN1TSHR | |
| SCHEMBL31490450 | 0.65 | IRAK4 (0.48) | HPGDNISCHKMT2AMEN1TSHR | |
| Ammonia Solution, Strong SCHEMBL5891986 | 0.64 | IRAK4 (0.47) | HPGDNISCHKMT2AMEN1TSHR | |
| SCHEMBL28883167 | 0.64 | IRAK4 (0.47) | HPGDNISCHKMT2AMEN1TSHR | |
| SCHEMBL11874440 | 0.64 | CES1 (0.50) | HPGDKMT2AMEN1TSHRL3MBTL1 | |
| Hydrochloric Acid SCHEMBL4624005 | 0.64 | IRAK4 (0.47) | HPGDNISCHKMT2AMEN1TSHR | |
| SCHEMBL28911420 | 0.63 | TSHR (0.46) | HPGDNISCHKMT2AMEN1TSHR | |
| SCHEMBL20282734 | 0.62 | NISCH (0.45) | HPGDNISCHKMT2AMEN1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4003915-A | ANTICONVULSANTS, PARKINSON*S DISEASE | HOFFMANN-LA ROCHE INC. (US) | 1977-01-18 | — | — | US | disclosed |