Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11758253 | 0.70 | ALDH1A1 (0.51) | HPGDCYP2C19ALDH1A1KMT2AMAPT | |
| SCHEMBL1592876 | 0.70 | TDP1 (0.60) | HPGDTSHRRAB9ANPC1TDP1 | |
| SCHEMBL8337448 | 0.70 | TDP1 (0.49) | HPGDTSHRRAB9ANPC1TDP1 | |
| SCHEMBL11757310 | 0.70 | CES1 (0.47) | HPGDTDP1CYP2C19ALDH1A1MAPT | |
| SCHEMBL11759686 | 0.70 | CES1 (0.47) | HPGDTDP1CYP2C19ALDH1A1L3MBTL1 | |
| SCHEMBL11782821 | 0.70 | HPGD (0.37) | HPGDTSHRRAB9ANPC1CYP2D6 | |
| SCHEMBL11755077 | 0.69 | HRH1 (0.53) | CYP2D6ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL11761593 | 0.69 | CYP3A4 (0.57) | TSHRRAB9ANPC1TDP1CYP2C19 | |
| SCHEMBL11760835 | 0.69 | HRH1 (0.43) | CYP2D6ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL11760838 | 0.69 | HRH1 (0.43) | CYP2D6ALDH1A1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4003915-A | ANTICONVULSANTS, PARKINSON*S DISEASE | HOFFMANN-LA ROCHE INC. (US) | 1977-01-18 | — | — | US | disclosed |