Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 2/20 | 0.46 |
| ▸ | ACKR3 | P25106 | 13/20 | 0.44 |
| ▸ | HTR1E | P28566 | 3/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1177898 | 0.90 | CYP1A2 (0.51) | PTGESACKR3HTR1ES1PR3MAPT | |
| Bicarbonate SCHEMBL3697013 | 0.86 | PTGES (0.50) | PTGESACKR3HTR1ES1PR3MAPT | |
| Bicarbonate SCHEMBL3706404 | 0.86 | PTGES (0.50) | PTGESACKR3HTR1ES1PR3MAPT | |
| SCHEMBL1178325 | 0.85 | PTGES (0.45) | PTGESACKR3HTR1ES1PR3MAPT | |
| SCHEMBL3706314 | 0.85 | PTGES (0.64) | PTGESHTR1ES1PR3MAPTMEN1 | |
| SCHEMBL1178778 | 0.84 | PTGES (0.45) | PTGESACKR3HTR1ES1PR3MAPT | |
| SCHEMBL3706401 | 0.83 | PTGES (0.48) | PTGESACKR3HTR1ES1PR3MAPT | |
| SCHEMBL3697010 | 0.83 | PTGES (0.48) | PTGESACKR3HTR1ES1PR3MAPT | |
| SCHEMBL1178322 | 0.83 | PTGES (0.51) | PTGESACKR3HTR1ES1PR3MAPT | |
| SCHEMBL3692778 | 0.83 | PTGES (0.44) | PTGESACKR3HTR1ES1PR3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110034450-A1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATIVES AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIEGESELLSCHAFT (DE) | 2011-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110034450-A1 | OXO-HETEROCYCLIC SUBSTITUTED CARBOXYLIC ACID DERIVATIVES AND THE USE THEREOF | OTC, PC, HCAR2 | PTGES 224/4885ACKR3 1783/4885HTR1E 4408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.