Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 1/20 | 0.58 |
| ▸ | BLM | P54132 | 1/20 | 0.58 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | CISD1 | Q9NZ45 | 8/20 | 0.48 |
| ▸ | AQP1 | P29972 | 1/20 | 0.45 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2741842 | 0.91 | CA2 (0.66) | CA2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL11780993 | 0.90 | CA2 (0.56) | CA2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL16581063 | 0.84 | CA2 (0.56) | CA2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL11779282 | 0.82 | CA2 (0.38) | CA2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL11779276 | 0.82 | CA2 (0.38) | CA2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL11777320 | 0.82 | CISD1 (0.49) | CA2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL16581178 | 0.81 | CA2 (0.53) | CA2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL11802231 | 0.80 | KDM4E (0.84) | CA2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL11804909 | 0.80 | CA2 (0.57) | CA2KDM4EUSP2ALDH1A1LMNA | |
| SCHEMBL11853823 | 0.80 | HPGD (0.54) | CA2KDM4EUSP2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933906-A | DIURETIC | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | claimed |
| US-3933906-A | DIURETIC | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |