Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 2/20 | 0.49 |
| ▸ | CA2 | P00918 | 10/20 | 0.44 |
| ▸ | CA12 | O43570 | 9/20 | 0.44 |
| ▸ | CA1 | P00915 | 9/20 | 0.44 |
| ▸ | CA9 | Q16790 | 8/20 | 0.44 |
| ▸ | CA3 | P07451 | 6/20 | 0.44 |
| ▸ | CA6 | P23280 | 6/20 | 0.44 |
| ▸ | CA7 | P43166 | 6/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 6/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.44 |
| ▸ | CA5B | Q9Y2D0 | 5/20 | 0.44 |
| ▸ | CA5A | P35218 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11841241 | 0.93 | CISD1 (0.53) | CISD1CA2CA12CA1CA9 | |
| SCHEMBL11853856 | 0.90 | CISD1 (0.54) | CISD1CA2CA12CA1CA9 | |
| SCHEMBL11846910 | 0.90 | CISD1 (0.48) | CISD1CA2CA12CA1CA9 | |
| SCHEMBL11784962 | 0.89 | L3MBTL1 (0.46) | CISD1ALDH1A1HPGDHSD17B10LMNA | |
| SCHEMBL11783802 | 0.89 | CISD1 (0.47) | CISD1CA2CA12CA1CA9 | |
| SCHEMBL11850459 | 0.88 | PPARA (0.46) | CISD1CA2CA12CA1CA9 | |
| SCHEMBL11849176 | 0.87 | MRGPRX4 (0.54) | CISD1CA2CA12CA1CA9 | |
| SCHEMBL11842259 | 0.86 | CISD1 (0.57) | CISD1CA2CA12CA1CA9 | |
| SCHEMBL11780992 | 0.86 | L3MBTL1 (0.41) | CISD1ALDH1A1HPGDHSD17B10KDM4E | |
| SCHEMBL11778805 | 0.85 | ALDH1A1 (0.53) | CISD1CA2CA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933906-A | DIURETIC | CIBA-GEIGY CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |