Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | CFTR | P13569 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11784648 | 0.89 | MAPT (0.46) | SMN1; SMN2ALDH1A1RAB9AMAPTNPC1 | |
| SCHEMBL11407603 | 0.83 | ADORA3 (0.44) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL11870798 | 0.83 | MAPT (0.39) | SMN1; SMN2MAPTPGRMEN1KMT2A | |
| SCHEMBL11880135 | 0.77 | CTSL (0.39) | ALDH1A1MAPTMEN1KMT2ALMNA | |
| SCHEMBL11872924 | 0.77 | CASR (0.48) | — | |
| SCHEMBL11410850 | 0.72 | NR1I2 (0.48) | MAPTPGRPDE4D | |
| SCHEMBL3522604 | 0.72 | NR1I2 (0.62) | PDE4D | |
| SCHEMBL11789237 | 0.71 | CASR (0.61) | RAB9AMAPTNPC1PDE4D | |
| SCHEMBL11817686 | 0.70 | NR1I2 (0.41) | ALDH1A1MAPTMEN1KMT2ACFTR | |
| SCHEMBL3521741 | 0.70 | CASR (0.50) | PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3997564-A | ANTIINFLAMMATORY | SANDOZ, INC. (US) | 1976-12-14 | — | — | US | disclosed |