Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1L1 | Q9UHC9 | 8/20 | 0.58 |
| ▸ | USP2 | O75604 | 2/20 | 0.55 |
| ▸ | VDR | P11473 | 1/20 | 0.55 |
| ▸ | CDC25A | P30304 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | POLA1 | P09884 | 2/20 | 0.54 |
| ▸ | FNTA | P49354 | 5/20 | 0.53 |
| ▸ | FNTB | P49356 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | TOP2A | P11388 | 1/20 | 0.50 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11786454 | 1.00 | NPC1L1 (0.58) | NPC1L1USP2VDRCDC25AMEN1 | |
| SCHEMBL11788002 | 0.90 | NPC1L1 (0.56) | NPC1L1USP2VDRCDC25APOLA1 | |
| SCHEMBL6393234 | 0.90 | NPC1L1 (0.56) | NPC1L1USP2VDRCDC25APOLA1 | |
| SCHEMBL25334704 | 0.89 | VDR (0.54) | NPC1L1USP2VDRCDC25APOLA1 | |
| SCHEMBL25334706 | 0.89 | VDR (0.54) | NPC1L1USP2VDRCDC25APOLA1 | |
| SCHEMBL11786843 | 0.89 | USP2 (0.51) | NPC1L1USP2VDRCDC25AMEN1 | |
| SCHEMBL11786829 | 0.89 | USP2 (0.51) | NPC1L1USP2VDRCDC25AMEN1 | |
| SCHEMBL21561555 | 0.87 | VDR (0.58) | USP2VDRPOLA1TOP2ATOP2B | |
| SCHEMBL11694285 | 0.84 | NPC1L1 (0.62) | NPC1L1USP2VDRCDC25AMEN1 | |
| SCHEMBL11845915 | 0.84 | NPC1L1 (0.75) | NPC1L1USP2VDRCDC25AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3963765-A | Preparation of derivatives of cholesterol | MAZUR YEHUDA | 1976-06-15 | — | — | US | claimed |