Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11791956 | 0.90 | MAPT (0.49) | MAPTALDH1A1KDM4ESMN1; SMN2NPC1 | |
| SCHEMBL11786058 | 0.85 | MAPT (0.47) | MAPTPKMCYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL11791815 | 0.84 | ALDH1A1 (0.44) | MAPTALDH1A1KDM4ESMN1; SMN2DHODH | |
| SCHEMBL11785559 | 0.84 | MAPT (0.59) | MAPTPKMALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11783528 | 0.82 | MAPT (0.43) | MAPTPKMALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL11787040 | 0.81 | MAPT (0.56) | MAPTPKMCYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL11834026 | 0.81 | MAPT (0.45) | MAPTPKMCYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL11787832 | 0.80 | RECQL (0.49) | MAPTPKMCYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL11783560 | 0.77 | HPGD (0.50) | ALDH1A1KDM4ESMN1; SMN2NPC1RAB9A | |
| SCHEMBL11788571 | 0.77 | MAPT (0.50) | MAPTALDH1A1KDM4ESMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954707-A | Polymers stabilized by bis(alkylsulfonyl)vinylanilines | AMERICAN CYANAMID COMPANY (US) | 1976-05-04 | — | — | US | disclosed |