Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11786964 | 0.81 | MAPT (0.53) | MAPTKEAP1PKMALDH1A1SMN1; SMN2 | |
| SCHEMBL10716650 | 0.78 | MAPT (0.78) | MAPTKEAP1PKMALDH1A1NPC1 | |
| SCHEMBL11786058 | 0.74 | MAPT (0.47) | MAPTPKMALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11834026 | 0.73 | MAPT (0.45) | MAPTPKMALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL5286296 | 0.72 | KEAP1 (0.52) | MAPTKEAP1PKMALDH1A1SMN1; SMN2 | |
| SCHEMBL10717891 | 0.72 | MAPT (1.00) | MAPTPKMALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL10412163 | 0.72 | ALDH1A1 (0.48) | MAPTPKMALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL28732796 | 0.70 | ALDH1A1 (0.46) | MAPTPKMALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL13103220 | 0.69 | ALDH1A1 (0.52) | MAPTPKMALDH1A1SMN1; SMN2NPC1 | |
| SCHEMBL4516541 | 0.69 | NAPRT (0.54) | MAPTALDH1A1SMN1; SMN2NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954707-A | Polymers stabilized by bis(alkylsulfonyl)vinylanilines | AMERICAN CYANAMID COMPANY (US) | 1976-05-04 | — | — | US | disclosed |