Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 10/20 | 0.38 |
| ▸ | CNR2 | P34972 | 9/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.38 |
| ▸ | KDR | P35968 | 3/20 | 0.37 |
| ▸ | ABHD12 | Q8N2K0 | 3/20 | 0.36 |
| ▸ | ABHD6 | Q9BV23 | 3/20 | 0.36 |
| ▸ | FAAH | O00519 | 2/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.36 |
| ▸ | GPR183 | P32249 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.36 |
| ▸ | GPR18 | Q14330 | 1/20 | 0.36 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11787542 | 0.80 | ALDH1A1 (0.46) | — | |
| SCHEMBL11795467 | 0.76 | DRD4 (0.40) | CNR1CNR2KDRGPR183 | |
| SCHEMBL11794440 | 0.74 | AKR1B1 (0.37) | CNR1CNR2OPRM1 | |
| SCHEMBL11787487 | 0.70 | CNR2 (0.39) | CNR1CNR2OPRM1 | |
| SCHEMBL11321070 | 0.68 | CNR2 (0.55) | CNR1CNR2OPRM1 | |
| SCHEMBL11787538 | 0.67 | KMT2A (0.42) | — | |
| SCHEMBL11774583 | 0.63 | CNR2 (0.56) | CNR1CNR2OPRM1 | |
| SCHEMBL11321088 | 0.63 | CNR2 (0.42) | CNR1CNR2OPRM1 | |
| SCHEMBL11773119 | 0.62 | CNR2 (0.47) | CNR1CNR2OPRM1 | |
| SCHEMBL31545533 | 0.62 | OPRM1 (0.54) | CNR1CNR2OPRM1ABHD12ABHD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3947462-A | 2,4,7-substituted 5-hydroxy benzopyrans and esters | ABBOTT LABORATORIES (US) | 1976-03-30 | — | — | US | disclosed |