Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CISD1 | Q9NZ45 | 7/20 | 0.53 |
| ▸ | CA2 | P00918 | 9/20 | 0.47 |
| ▸ | CA12 | O43570 | 7/20 | 0.47 |
| ▸ | CA1 | P00915 | 7/20 | 0.47 |
| ▸ | CA6 | P23280 | 7/20 | 0.47 |
| ▸ | CA7 | P43166 | 7/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 7/20 | 0.47 |
| ▸ | CA5A | P35218 | 6/20 | 0.47 |
| ▸ | CA9 | Q16790 | 6/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 6/20 | 0.47 |
| ▸ | CA4 | P22748 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.47 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.47 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 6/20 | 0.44 |
| ▸ | CA13 | Q8N1Q1 | 6/20 | 0.44 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11802842 | 0.92 | CISD1 (0.47) | CISD1CA2CA12CA1CA6 | |
| SCHEMBL11705514 | 0.88 | CISD1 (0.67) | CISD1CA2CA12CA1CA6 | |
| SCHEMBL11844344 | 0.86 | CISD1 (0.41) | CISD1CA2CA12CA1CA6 | |
| SCHEMBL11710582 | 0.84 | CISD1 (0.58) | CISD1CA2CA12CA1CA6 | |
| SCHEMBL11838989 | 0.83 | MEN1 (0.39) | CISD1ALDH1A1LMNATSHRCYP2C9 | |
| SCHEMBL11056311 | 0.83 | CISD1 (0.69) | CISD1CA2CA12CA1CA6 | |
| SCHEMBL11709830 | 0.82 | CISD1 (0.62) | CISD1CA2CA12CA1CA6 | |
| SCHEMBL11790756 | 0.82 | CISD1 (0.58) | CISD1CA2CA12CA1CA6 | |
| SCHEMBL22515417 | 0.81 | CISD1 (0.73) | CISD1CA2CA12CA1CA6 | |
| SCHEMBL11708093 | 0.81 | CISD1 (0.69) | CISD1CA2CA12CA1CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3985777-A | Sulphamyl-benzoic acid derivatives | LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB (DK) | 1976-10-12 | — | — | US | claimed |
| US-3991097-A | BORON HYDRIDE OR METAL BOROHYDRIDES AS REDUCING AGENT, LEWIS ACID | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-11-09 | — | — | US | disclosed |
| US-3985777-A | Sulphamyl-benzoic acid derivatives | LOVENS KEMISKE FABRIK PRODUKTIONSAKTIESELSKAB (DK) | 1976-10-12 | — | — | US | disclosed |