Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11844344 | 0.88 | CISD1 (0.41) | MEN1KMT2ACISD1CYP2C9CYP1A2 | |
| SCHEMBL11796943 | 0.84 | BRAF (0.37) | MEN1KMT2ACISD1APPLMNA | |
| SCHEMBL11777207 | 0.83 | SIRT2 (0.39) | MEN1KMT2ACISD1NPC1RAB9A | |
| SCHEMBL11788087 | 0.83 | CISD1 (0.53) | CISD1CYP2C9LMNATSHRALDH1A1 | |
| SCHEMBL11802842 | 0.76 | CISD1 (0.47) | CISD1APPALDH1A1 | |
| SCHEMBL11842089 | 0.72 | LMNA (0.51) | MEN1KMT2APKMLMNATSHR | |
| Acetanilide SCHEMBL11798783 | 0.72 | CISD1 (0.49) | CISD1APPALDH1A1 | |
| SCHEMBL11705514 | 0.71 | CISD1 (0.67) | MEN1KMT2ACISD1CYP2C9LMNA | |
| SCHEMBL11820413 | 0.70 | CISD1 (0.45) | MEN1KMT2ACISD1APPTSHR | |
| SCHEMBL11781753 | 0.70 | CISD1 (0.41) | CISD1APPSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3939267-A | DIURETIC | CIBA-GEIGY CORPORATION (US) | 1976-02-17 | — | — | US | disclosed |