Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 6/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | HTR1D | P28221 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.49 |
| ▸ | HTR3A | P46098 | 1/20 | 0.49 |
| ▸ | HTR6 | P50406 | 1/20 | 0.49 |
| ▸ | SPR | P35270 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19788888 | 0.82 | TDP1 (0.55) | RAD52BLMNPSR1GAAHSD17B10 | |
| SCHEMBL5116957 | 0.81 | AKR1C2 (0.58) | GAAHSD17B10TDP1HTR1DMAPK1 | |
| SCHEMBL3385819 | 0.74 | GAA (0.66) | RAD52BLMNPSR1GAAHSD17B10 | |
| SCHEMBL852745 | 0.72 | HSD17B10 (0.67) | RAD52BLMNPSR1GAAHSD17B10 | |
| SCHEMBL4377509 | 0.71 | KDM4E (0.58) | RAD52BLMNPSR1GAAHSD17B10 | |
| SCHEMBL28709106 | 0.71 | TDP1 (0.57) | RAD52BLMNPSR1GAAHSD17B10 | |
| SCHEMBL6222643 | 0.71 | NPSR1 (0.51) | BLMNPSR1HSD17B10TDP1CYP1A2 | |
| SCHEMBL2003333 | 0.71 | KDM4E (0.75) | RAD52BLMNPSR1GAAHSD17B10 | |
| SCHEMBL11788979 | 0.71 | HTR7 (0.65) | RAD52BLMNPSR1GAAHSD17B10 | |
| SCHEMBL7815779 | 0.71 | GAA (0.68) | RAD52BLMNPSR1GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3959270-A | DIURETICS, ANTIHYPERTENSIVE, ANTIULCER, ANTIINFLAMMATORY, SEDATIVES, ANALGESICS | DELALANDE S.A. (FR) | 1976-05-25 | — | — | US | disclosed |