Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 5/20 | 0.56 |
| ▸ | ADRB1 | P08588 | 5/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.56 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | CNR1 | P21554 | 1/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | THPO | P40225 | 1/20 | 0.56 |
| ▸ | BLM | P54132 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.54 |
| ▸ | CYP2J2 | P51589 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11788885 | 0.87 | ADRB2 (0.53) | ADRB2ADRB1TDP1LMNAADRA1A | |
| SCHEMBL11226933 | 0.86 | ADRB2 (0.66) | ADRB2ADRB1TDP1LMNAADRA1A | |
| SCHEMBL10714150 | 0.80 | ADRB2 (0.49) | ADRB2ADRB1TDP1LMNAADRA1A | |
| SCHEMBL10716097 | 0.80 | ADRB2 (0.49) | ADRB2ADRB1TDP1LMNAADRA1A | |
| SCHEMBL11793508 | 0.80 | ADRB2 (0.56) | ADRB2ADRB1TDP1ADRA1APMP22 | |
| SCHEMBL11791015 | 0.79 | KMT2A (0.65) | ADRB2ADRB1TDP1ADRA1APMP22 | |
| SCHEMBL11712662 | 0.79 | ADRB2 (0.49) | ADRB2ADRB1TDP1LMNAADRA1A | |
| SCHEMBL11714832 | 0.79 | ADRB2 (0.49) | ADRB2ADRB1TDP1LMNAADRA1A | |
| SCHEMBL11712653 | 0.79 | ADRB2 (0.49) | ADRB2ADRB1TDP1LMNAADRA1A | |
| SCHEMBL11791196 | 0.78 | ABCB1 (0.60) | ADRB2ADRB1TDP1LMNAADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3949088-A | Substituted phenoxy propanol amines used for treating cardiovascular diseases | SAMUELSSON BENNY ROGER | 1976-04-06 | — | — | US | claimed |
| US-3949088-A | Substituted phenoxy propanol amines used for treating cardiovascular diseases | SAMUELSSON BENNY ROGER | 1976-04-06 | — | — | US | disclosed |