Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11802232 | 0.87 | MAPT (0.51) | MAPTTHRBALDH1A1KMT2AMEN1 | |
| SCHEMBL1717514 | 0.84 | NPSR1 (0.51) | NPSR1MAPTTP53THRBALDH1A1 | |
| SCHEMBL11793691 | 0.82 | THRB (0.55) | MAPTTHRBALDH1A1KMT2AMEN1 | |
| SCHEMBL11789226 | 0.81 | MAPT (0.60) | MAPTTP53THRBALDH1A1KMT2A | |
| SCHEMBL11789135 | 0.78 | POLB (0.51) | NPSR1MAPTALDH1A1KMT2AMEN1 | |
| SCHEMBL11792085 | 0.77 | MAPT (0.50) | MAPTTP53THRBALDH1A1KMT2A | |
| SCHEMBL1716858 | 0.75 | TP53 (0.51) | MAPTTP53THRBALDH1A1KMT2A | |
| SCHEMBL11796475 | 0.75 | MAPT (0.58) | NPSR1MAPTTP53ALDH1A1KMT2A | |
| SCHEMBL1996045 | 0.74 | CA12 (0.66) | MAPTTP53THRBALDH1A1KMT2A | |
| SCHEMBL21257527 | 0.74 | MAPT (0.55) | NPSR1MAPTTP53THRBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3978072-A | ANTIINFLAMMATORY | ABIC LTD. (IL) | 1976-08-31 | — | — | US | disclosed |