Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.44 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21257531 | 0.79 | MAPT (0.50) | MAPTNPC1RAB9AMAPK1NPSR1 | |
| SCHEMBL21257521 | 0.78 | MAPT (0.52) | MAPTNPC1RAB9AMAPK1NPSR1 | |
| SCHEMBL17172478 | 0.75 | MAPK1 (0.60) | MAPTNPC1RAB9AMAPK1NPSR1 | |
| SCHEMBL3702377 | 0.74 | NPSR1 (0.59) | MAPTNPC1RAB9ANPSR1ALDH1A1 | |
| SCHEMBL11790767 | 0.74 | NPSR1 (0.55) | MAPTNPC1RAB9AMAPK1NPSR1 | |
| SCHEMBL19808418 | 0.73 | MAPT (0.57) | MAPTNPC1RAB9AMAPK1NPSR1 | |
| SCHEMBL2325118 | 0.73 | TSHR (0.74) | MAPTNPC1RAB9ANPSR1TSHR | |
| SCHEMBL29604433 | 0.73 | TSHR (0.74) | MAPTNPC1RAB9ANPSR1TSHR | |
| SCHEMBL18867935 | 0.73 | TSHR (0.74) | MAPTNPC1RAB9ANPSR1TSHR | |
| SCHEMBL15714567 | 0.73 | MAPT (0.54) | MAPTNPC1RAB9AMAPK1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019154366-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREOF | 江苏奥赛康药业有限公司 | 2019-08-15 | — | — | WO | disclosed |