Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9294948 | 0.85 | TRPA1 (0.55) | GRM1KMT2ATDP1MEN1CYP1A2 | |
| SCHEMBL25362682 | 0.81 | MEN1 (0.68) | GRM1KMT2ATDP1MEN1CYP1A2 | |
| SCHEMBL8615977 | 0.81 | MEN1 (0.68) | GRM1KMT2ATDP1MEN1CYP1A2 | |
| SCHEMBL9988672 | 0.79 | CSNK2A1 (0.50) | KMT2ATDP1MEN1CSNK2A1ALDH1A1 | |
| SCHEMBL25894342 | 0.79 | GRM1 (0.69) | GRM1KMT2ATDP1MEN1CYP1A2 | |
| SCHEMBL9988669 | 0.79 | CSNK2A1 (0.50) | KMT2ATDP1MEN1CSNK2A1ALDH1A1 | |
| SCHEMBL17774725 | 0.79 | KDM4E (0.50) | GRM1KMT2ATDP1MEN1CYP1A2 | |
| SCHEMBL18361419 | 0.78 | MEN1 (0.50) | GRM1KMT2ATDP1MEN1CYP1A2 | |
| SCHEMBL8622029 | 0.78 | MEN1 (0.54) | GRM1KMT2ATDP1MEN1CYP1A2 | |
| SCHEMBL18360859 | 0.78 | MEN1 (0.50) | GRM1KMT2ATDP1MEN1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3993665-A | 3-Amidocoumaranones | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |
| US-3993666-A | Coumaranedione-3-monoximes | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-23 | — | — | US | disclosed |