Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11797014 | 0.89 | HTT (0.48) | KMT2AALDH1A1NPSR1KDM4ELMNA | |
| SCHEMBL11793999 | 0.88 | ALDH1A1 (0.41) | KMT2AALDH1A1KDM4ELMNATSHR | |
| SCHEMBL11788809 | 0.84 | ALDH1A1 (0.37) | KMT2AALDH1A1POLBLMNATSHR | |
| SCHEMBL11798036 | 0.82 | PPIA (0.41) | KMT2ALMNATSHRL3MBTL1 | |
| SCHEMBL11791704 | 0.80 | KDM4E (0.41) | KMT2AALDH1A1MAPK1NPSR1KDM4E | |
| SCHEMBL11797983 | 0.80 | CHRM5 (0.43) | KMT2AALDH1A1MAPK1NPSR1KDM4E | |
| SCHEMBL11790071 | 0.79 | ALDH1A1 (0.52) | KMT2AALDH1A1KDM4EPOLBLMNA | |
| SCHEMBL11790788 | 0.77 | MAPT (0.55) | KMT2AALDH1A1LMNASMN1; SMN2MEN1 | |
| SCHEMBL11789560 | 0.77 | CYP1A2 (0.45) | ALDH1A1KDM4EPOLBTSHRL3MBTL1 | |
| SCHEMBL11796546 | 0.77 | KMT2A (0.45) | KMT2AALDH1A1MAPK1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3998954-A | 1,3(2H,4H)-Dioxoisoquinoline-4-carboxamides used as anti-inflammatory agents | PFIZER INC. (US) | 1976-12-21 | — | — | US | disclosed |