Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.77 |
| ▸ | USP2 | O75604 | 1/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.77 |
| ▸ | CA2 | P00918 | 1/20 | 0.77 |
| ▸ | LMNA | P02545 | 1/20 | 0.77 |
| ▸ | HPGD | P15428 | 1/20 | 0.77 |
| ▸ | TSHR | P16473 | 1/20 | 0.77 |
| ▸ | BLM | P54132 | 1/20 | 0.77 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.77 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.77 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.77 |
| ▸ | AQP1 | P29972 | 1/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 15/20 | 0.63 |
| ▸ | STS | P08842 | 2/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11787813 | 0.99 | KDM4E (0.78) | KDM4EUSP2ALDH1A1CA2LMNA | |
| SCHEMBL11842239 | 0.97 | KDM4E (0.75) | KDM4EUSP2ALDH1A1CA2LMNA | |
| SCHEMBL2876098 | 0.96 | KDM4E (0.80) | KDM4EUSP2ALDH1A1CA2LMNA | |
| SCHEMBL230777 | 0.93 | KDM4E (0.72) | KDM4EUSP2ALDH1A1CA2LMNA | |
| SCHEMBL11784497 | 0.91 | KDM4E (0.81) | KDM4EUSP2ALDH1A1CA2LMNA | |
| SCHEMBL22971474 | 0.91 | KDM4E (0.81) | KDM4EUSP2ALDH1A1CA2LMNA | |
| SCHEMBL29436047 | 0.91 | LMNA (0.72) | KDM4EUSP2ALDH1A1CA2LMNA | |
| SCHEMBL231315 | 0.91 | CA2 (0.74) | KDM4EUSP2ALDH1A1CA2LMNA | |
| SCHEMBL23432111 | 0.90 | LMNA (0.73) | KDM4EUSP2ALDH1A1CA2LMNA | |
| SCHEMBL22971169 | 0.90 | KDM4E (0.73) | KDM4EUSP2ALDH1A1CA2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3991097-A | BORON HYDRIDE OR METAL BOROHYDRIDES AS REDUCING AGENT, LEWIS ACID | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-11-09 | — | — | US | disclosed |