Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 13/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 12/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 8/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2216041 | 0.87 | NPC1 (0.56) | HDAC6HDAC1ALDH1A1NPC1RAB9A | |
| SCHEMBL11666718 | 0.79 | HDAC6 (0.41) | HDAC6HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL1412848 | 0.79 | KDM4E (0.59) | HDAC6HDAC1HDAC8HDAC3NPC1 | |
| SCHEMBL17072356 | 0.76 | HDAC3 (0.56) | HDAC6HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL31377918 | 0.76 | P2RX7 (0.52) | ALDH1A1GAAKDM4ESIRT6POLB | |
| SCHEMBL26697541 | 0.75 | HDAC1 (0.47) | HDAC6HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL22270446 | 0.75 | HDAC1 (0.50) | HDAC6HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL7278412 | 0.74 | P4HTM (0.68) | HDAC6HDAC1HDAC8HDAC3HDAC4 | |
| SCHEMBL18530692 | 0.73 | SMN1; SMN2 (0.68) | HDAC8ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18530688 | 0.73 | SMN1; SMN2 (0.68) | HDAC8ALDH1A1NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3954718-A | Process for preparing polymers containing carbamoyl-hydroxamate groups and the resultant polymers | STANFORD RESEARCH INSTITUTE (US) | 1976-05-04 | — | — | US | disclosed |