Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 7/20 | 0.59 |
| ▸ | MEN1 | O00255 | 6/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 5/20 | 0.56 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | PNLIP | P16233 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11791558 | 0.89 | MEN1 (0.57) | LMNAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL14338360 | 0.85 | TSHR (0.69) | LMNAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL11788972 | 0.84 | LMNA (0.64) | LMNAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL11789596 | 0.82 | MAPT (0.58) | KMT2ANPC1RAB9ATSHRSMN1; SMN2 | |
| SCHEMBL6778518 | 0.78 | LMNA (0.76) | LMNAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL23796819 | 0.78 | SMN1; SMN2 (0.58) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL30031490 | 0.78 | SMN1; SMN2 (0.58) | MEN1KMT2ANPC1RAB9ASMN1; SMN2 | |
| 4-Methoxydianthramide B SCHEMBL31238353 | 0.77 | NPC1 (0.70) | LMNAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL18327174 | 0.77 | LMNA (0.89) | LMNAMEN1KMT2ANPC1RAB9A | |
| SCHEMBL10763914 | 0.76 | KMT2A (0.69) | LMNAMEN1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3953496-A | ANTIPYRETICS, ANTI-ALLERGIC, ANTI-INFLAMMATORY AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) | 1976-04-27 | — | — | US | claimed |
| US-3953496-A | ANTIPYRETICS, ANTI-ALLERGIC, ANTI-INFLAMMATORY AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) | 1976-04-27 | — | — | US | disclosed |