Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.63 |
| ▸ | MEN1 | O00255 | 3/20 | 0.63 |
| ▸ | TP53 | P04637 | 3/20 | 0.63 |
| ▸ | HTT | P42858 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | PNLIP | P16233 | 2/20 | 0.56 |
| ▸ | FADS1 | O60427 | 1/20 | 0.56 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10763914 | 0.89 | KMT2A (0.69) | LMNAKMT2AMEN1TP53HTT | |
| SCHEMBL10615518 | 0.88 | LMNA (0.63) | LMNAKMT2AMEN1TP53HTT | |
| SCHEMBL29375984 | 0.88 | LMNA (0.63) | LMNAKMT2AMEN1TP53HTT | |
| SCHEMBL6093462 | 0.88 | GFER (0.69) | LMNAKMT2AMEN1TP53HTT | |
| SCHEMBL2133475 | 0.84 | KMT2A (0.74) | LMNAKMT2AMEN1TP53HTT | |
| SCHEMBL11792714 | 0.84 | LMNA (0.59) | LMNAKMT2AMEN1TP53HTT | |
| SCHEMBL4669122 | 0.84 | LMNA (0.76) | LMNAKMT2AMEN1TP53HTT | |
| SCHEMBL11405554 | 0.84 | LMNA (0.76) | LMNAKMT2AMEN1TP53HTT | |
| SCHEMBL14075282 | 0.82 | ALOX15 (0.66) | LMNAKMT2AMEN1TP53HTT | |
| SCHEMBL6093021 | 0.80 | LMNA (0.60) | LMNAKMT2AMEN1TP53HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3953496-A | ANTIPYRETICS, ANTI-ALLERGIC, ANTI-INFLAMMATORY AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) | 1976-04-27 | — | — | US | claimed |
| US-3953496-A | ANTIPYRETICS, ANTI-ALLERGIC, ANTI-INFLAMMATORY AGENTS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) | 1976-04-27 | — | — | US | disclosed |