Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.43 |
| ▸ | CPT2 | P23786 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.39 |
| ▸ | ACACB | O00763 | 1/20 | 0.38 |
| ▸ | ACACA | Q13085 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11795766 | 0.84 | ACACB (0.60) | FFAR1FFAR4GPR84ACACBACACA | |
| SCHEMBL11786556 | 0.82 | FFAR1 (0.45) | FFAR1CPT2TDP1FFAR4GPR84 | |
| SCHEMBL11603619 | 0.81 | FFAR1 (0.44) | FFAR1CPT2TDP1FFAR4GPR84 | |
| SCHEMBL11792910 | 0.81 | FFAR1 (0.44) | FFAR1CPT2TDP1FFAR4GPR84 | |
| SCHEMBL11795536 | 0.81 | FFAR4 (0.67) | FFAR1TDP1FFAR4GPR84FAAH | |
| SCHEMBL11793908 | 0.81 | FFAR4 (0.67) | FFAR1TDP1FFAR4GPR84FAAH | |
| SCHEMBL11799508 | 0.79 | GPR84 (0.49) | FFAR1FFAR4GPR84NFKB1FAAH | |
| SCHEMBL11790456 | 0.78 | ACE2 (0.50) | FFAR1FFAR4GPR84NFKB1FAAH | |
| SCHEMBL12094526 | 0.78 | FFAR1 (0.69) | FFAR1CPT2TDP1FFAR4GPR84 | |
| SCHEMBL12094522 | 0.77 | FFAR1 (0.73) | FFAR1CPT2TDP1FFAR4GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3989749-A | RENAL VASODILATORS, ANTITHROMBUS | MERCK & CO., INC. (US) | 1976-11-02 | — | — | US | disclosed |