Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.33 |
| ▸ | PTGFR | P43088 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11790456 | 0.84 | ACE2 (0.50) | GPR84FFAR1FFAR4ACE2NFKB1 | |
| SCHEMBL11795536 | 0.84 | FFAR4 (0.67) | GPR84FFAR1FFAR4FAAHTBXA2R | |
| SCHEMBL11793908 | 0.84 | FFAR4 (0.67) | GPR84FFAR1FFAR4FAAHTBXA2R | |
| SCHEMBL11784233 | 0.81 | GPR84 (0.51) | GPR84FFAR1FFAR4ACE2NFKB1 | |
| SCHEMBL11604151 | 0.80 | GPR84 (0.50) | GPR84FFAR1FFAR4ACE2NFKB1 | |
| SCHEMBL11792806 | 0.80 | GPR84 (0.50) | GPR84FFAR1FFAR4ACE2NFKB1 | |
| SCHEMBL11800869 | 0.80 | FFAR4 (0.42) | GPR84FFAR1FFAR4NFKB1FAAH | |
| SCHEMBL11792913 | 0.79 | FFAR1 (0.43) | GPR84FFAR1FFAR4NFKB1FAAH | |
| SCHEMBL11795766 | 0.77 | ACACB (0.60) | GPR84FFAR1FFAR4ACE2NFKB1 | |
| SCHEMBL30882121 | 0.76 | GPR84 (0.61) | GPR84FFAR1FFAR4ACE2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3989749-A | RENAL VASODILATORS, ANTITHROMBUS | MERCK & CO., INC. (US) | 1976-11-02 | — | — | US | disclosed |