Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.49 |
| ▸ | FAAH | O00519 | 2/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11796421 | 0.87 | ACE2 (0.51) | ACE2FFAR1FFAR4FAAHGPR84 | |
| SCHEMBL11783707 | 0.85 | FFAR4 (0.71) | FFAR1FFAR4FAAHGPR84PPARD | |
| SCHEMBL11783701 | 0.85 | FFAR4 (0.71) | FFAR1FFAR4FAAHGPR84PPARD | |
| SCHEMBL11784174 | 0.85 | FFAR4 (0.71) | FFAR1FFAR4FAAHGPR84PPARD | |
| SCHEMBL11783712 | 0.85 | FFAR4 (0.71) | FFAR1FFAR4FAAHGPR84PPARD | |
| SCHEMBL8586725 | 0.84 | ACE2 (0.71) | ACE2FFAR1FFAR4FAAHGPR84 | |
| SCHEMBL293989 | 0.84 | ACE2 (0.71) | ACE2FFAR1FFAR4FAAHGPR84 | |
| SCHEMBL13730236 | 0.84 | ACE2 (0.71) | ACE2FFAR1FFAR4FAAHGPR84 | |
| SCHEMBL11784233 | 0.83 | GPR84 (0.51) | ACE2FFAR1FFAR4FAAHGPR84 | |
| SCHEMBL11602265 | 0.81 | ACE2 (0.51) | ACE2FFAR1FFAR4FAAHGPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3987091-A | RENAL VASODILATORS | MERCK & CO., INC. (US) | 1976-10-19 | — | — | US | disclosed |