Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.71 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.66 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.66 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.62 |
| ▸ | FAAH | O00519 | 2/20 | 0.60 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | LCK | P06239 | 1/20 | 0.53 |
| ▸ | PPARD | Q03181 | 1/20 | 0.53 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.53 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8586725 | 1.00 | ACE2 (0.71) | ACE2FFAR1FFAR4GPR84FAAH | |
| SCHEMBL293989 | 1.00 | ACE2 (0.71) | ACE2FFAR1FFAR4GPR84FAAH | |
| SCHEMBL12092729 | 0.96 | ACE2 (0.66) | ACE2FFAR1FFAR4GPR84FAAH | |
| SCHEMBL545070 | 0.94 | ACE2 (0.80) | ACE2FFAR1FFAR4GPR84FAAH | |
| SCHEMBL7146627 | 0.94 | ACE2 (0.80) | ACE2FFAR1FFAR4GPR84FAAH | |
| SCHEMBL2054033 | 0.94 | ACE2 (0.80) | ACE2FFAR1FFAR4GPR84FAAH | |
| Dodecane SCHEMBL14691319 | 0.94 | ACE2 (0.80) | ACE2FFAR1FFAR4GPR84FAAH | |
| SCHEMBL277986 | 0.94 | ACE2 (0.80) | ACE2FFAR1FFAR4GPR84FAAH | |
| SCHEMBL7080552 | 0.94 | ACE2 (0.80) | ACE2FFAR1FFAR4GPR84FAAH | |
| SCHEMBL247871 | 0.94 | ACE2 (0.80) | ACE2FFAR1FFAR4GPR84FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10292994-B2 | Bioactive fractions and compounds from Dalbergia sissoo for the prevention or treatment of osteo-health related disorders | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2019-05-21 | — | — | US | disclosed |
| EP-2705047-B1 | BIOACTIVE FRACTIONS AND COMPOUNDS FROM DALBERGIA SISSOO FOR THE PREVENTION OR TREATMENT OF OSTEO-HEALTH RELATED DISORDERS | COUNCIL SCIENT IND RES (IN) | 2015-08-05 | — | — | EP | disclosed |
| US-20140079834-A1 | BIOACTIVE FRACTIONS AND COMPOUNDS FROM DALBERGIA SISSOO FOR THE PREVENTION OR TREATMENT OF OSTEO-HEALTH RELATED DISORDERS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-03-20 | — | — | US | disclosed |
| EP-2705047-A1 | BIOACTIVE FRACTIONS AND COMPOUNDS FROM DALBERGIA SISSOO FOR THE PREVENTION OR TREATMENT OF OSTEO-HEALTH RELATED DISORDERS | Council of Scientific and Industrial Research (IN) | 2014-03-12 | — | — | EP | disclosed |
| WO-2012147102-A1 | BIOACTIVE FRACTIONS AND COMPOUNDS FROM DALBERGIA SISSOO FOR THE PREVENTION OR TREATMENT OF OSTEO-HEALTH RELATED DISORDERS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-11-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140079834-A1 | BIOACTIVE FRACTIONS AND COMPOUNDS FROM DALBERGIA SISSOO FOR THE PREVENTION OR TREATMENT OF OSTEO-HEALTH RELATED DISORDERS | SOST, SHBG, ESR2 | ACE2 1902/4885FFAR1 1725/4885FFAR4 1475/4885 |
| US-10292994-B2 | Bioactive fractions and compounds from Dalbergia sissoo for the prevention or treatment of osteo-health related disorders | SOST, SHBG, ESR2 | ACE2 1902/4885FFAR1 1725/4885FFAR4 1475/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.