SCHEMBL1179382

SCHEMBL1179382

OCCOC(CCCOCCCC(OCCO)OCCO)OCCO

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.43
MAPK1 P28482 1/20 0.43
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
THRB P10828 1/20 0.38
HTT P42858 1/20 0.38
MAPT P10636 1/20 0.38
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11099712 0.87 TSHR (0.35) TSHRMAPK1MEN1KMT2A
SCHEMBL5878438 0.84 TSHR (0.33) TSHRMAPK1MEN1KMT2A
SCHEMBL20357811 0.84 TSHR (0.47) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL431930 0.82 TSHR (0.52) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL7193870 0.82 TSHR (0.32) TSHRMAPK1MEN1KMT2A
SCHEMBL21402309 0.82 TSHR (0.33) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL11291333 0.81 MEN1 (0.45) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL8866537 0.78 TSHR (0.52) TSHRMEN1KMT2ATHRBHTT
SCHEMBL14329925 0.78 TSHR (0.57) TSHRMAPK1MEN1KMT2ATHRB
SCHEMBL11099856 0.76 TSHR (0.30) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160152926-A1 PHOTORESIST REMOVAL ENTEGRIS, INC. 2016-06-02 US claimed
US-20080207814-A1 Thermally conductive adhesive composition and process for device attachment AGUILA TECHNOLOGIES, INC. (US) 2008-08-28 US claimed
US-7249723-B2 Organic solvent dispersed nano-talc slurry NGX, INC. (US) 2007-07-31 US claimed
WO-2007024252-A2 ORGANIC SOLVENT DISPERSED NANO-TALC SLURRY NANOMAT, INC. (US) 2007-03-01 WO claimed
US-20060086837-A1 Dry milling talc powder, mixing the dry-milled nano-talc powder with an organic solvent andwet milling the nano-talc-solvent mix NGX, INC. 2006-04-27 US claimed
US-6522524-B1 Ethylene glycol, aliphatic dicarboxylic acid, amine, and mannitol; cardiverter defibrillators PACESETTER, INC. 2003-02-18 US claimed
US-6517665-B1 Liga developer apparatus system SANDIA NATIONAL LABORATORIES 2003-02-11 US claimed
US-20200377450-A1 Surfactants From Sulfonation Of Aromatic Ethers EXXONMOBIL RES & ENG CO (US) 2020-12-03 US disclosed
EP-3374475-B1 LOW VISCOSITY LOW VOLATILITY LUBRICATING OIL BASE STOCKS AND PROCESSES FOR PREPARING SAME EXXONMOBIL RES & ENG CO (US) 2020-02-19 EP disclosed
EP-3611228-A1 ASSOCIATIVE POLYMERS AND RELATED COMPOSITIONS, METHODS AND SYSTEMS California Institute of Technology (US) 2020-02-19 EP disclosed
US-10323203-B2 Low viscosity, low volatility lubricating oil basestocks EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2019-06-18 US disclosed
US-10316712-B2 Lubricant compositions for surface finishing of materials EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2019-06-11 US disclosed
EP-3389902-A1 LUBRICANT COMPOSITIONS FOR SURFACE FINISHING OF MATERIALS ExxonMobil Research and Engineering Company (US) 2018-10-24 EP disclosed
US-20030211425-A1 Photoimageable, aqueous acid soluble polyimide polymers 3M INNOVATIVE PROPERTIES COMPANY 2003-11-13 US disclosed
US-20030098772-A1 Carbon monoxide detector CATALYTIC ELECTRODES LIMITED (GB) 2003-05-29 US disclosed
US-6569822-B1 Concentrate of acetates of N-coco-, N-oleyl- or N-tallow-1,3-diaminopropanes, alcohol, water, and a dissolving agent such as ethylene glycol, that passes a simple dilution test; use lubricating bottles on conveyor lines ATOFINA (FR) 2003-05-27 US disclosed
US-6522524-B1 Ethylene glycol, aliphatic dicarboxylic acid, amine, and mannitol; cardiverter defibrillators PACESETTER, INC. 2003-02-18 US disclosed
US-6517665-B1 Liga developer apparatus system SANDIA NATIONAL LABORATORIES 2003-02-11 US disclosed
US-6451743-B1 ADDITIVES FOR WATER-BASED DRILLING AND MINING FLUIDS; NONAQUEOUS MEDIUM IS GLYCOLS, POLYGLYCOLS, GLYCOL ETHERS OR ESTERS; SUSPENSION AID IS HYDROXYPROPYL CELLULOSE, ETHYL CELLULOSE, POLYVINYL PYRROLIDONE, POLYACRYLIC ACID CHEVRON PHILLIPS CHEMICAL COMPANY LP 2002-09-17 US disclosed
WO-2001055710-A1 CARBON MONOXIDE DETECTOR CATALYTIC ELECTRODES LIMITED (GB) 2001-08-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200377450-A1 Surfactants From Sulfonation Of Aromatic Ethers ARSA, ALK, STS TSHR 1955/4885MAPK1 1238/4885MEN1 4447/4885
US-10323203-B2 Low viscosity, low volatility lubricating oil basestocks TYK2, AHR, CEL TSHR 3136/4885MAPK1 478/4885MEN1 4492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.