Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11795382 | 1.00 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10HPGDALOX15 | |
| SCHEMBL11694355 | 0.81 | ALDH1A1 (0.59) | ALDH1A1LMNAHSD17B10HPGDALOX15 | |
| SCHEMBL11737599 | 0.81 | ALDH1A1 (0.51) | ALDH1A1LMNAHSD17B10HPGDALOX15 | |
| SCHEMBL11737604 | 0.81 | ALDH1A1 (0.51) | ALDH1A1LMNAHSD17B10HPGDALOX15 | |
| SCHEMBL11737225 | 0.78 | ALDH1A1 (0.57) | ALDH1A1LMNAHSD17B10HPGDALOX15 | |
| SCHEMBL11737230 | 0.78 | ALDH1A1 (0.57) | ALDH1A1LMNAHSD17B10HPGDALOX15 | |
| SCHEMBL11655475 | 0.76 | ALDH1A1 (0.49) | ALDH1A1LMNAHSD17B10HPGDALOX15 | |
| SCHEMBL11694686 | 0.75 | EPHX1 (0.51) | ALDH1A1LMNAHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL11884603 | 0.75 | HSD17B10 (0.51) | ALDH1A1LMNAHSD17B10HPGDALOX15 | |
| SCHEMBL11732603 | 0.74 | ALDH1A1 (0.66) | ALDH1A1LMNAHSD17B10HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4018926-A | Alkyl 4-[o-(substituted methyleneamino)-phenyl]-3-thioallophanate miticides and fungicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-04-19 | — | — | US | disclosed |
| US-4011213-A | FUNGICIDES, MITE OVICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1977-03-08 | — | — | US | disclosed |
| US-3958007-A | FUNGICIDES, MITE OVICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-05-18 | — | — | US | disclosed |