SCHEMBL11694355

SCHEMBL11694355

C=CCOC(=O)NC(=S)Nc1ccccc1NC(=S)NC(=O)OCC=C

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.59
HSD17B10 Q99714 3/20 0.59
LMNA P02545 2/20 0.59
HPGD P15428 1/20 0.59
ALOX15 P16050 1/20 0.59
KMT2A Q03164 4/20 0.50
MEN1 O00255 3/20 0.50
CYP3A4 P08684 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.43
EPHX1 P07099 1/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
KDM4E B2RXH2 1/20 0.41
MAPK1 P28482 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
TSHR P16473 1/20 0.41
POLB P06746 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11884603 0.92 HSD17B10 (0.51) ALDH1A1HSD17B10LMNAHPGDALOX15
SCHEMBL11655475 0.90 ALDH1A1 (0.49) ALDH1A1HSD17B10LMNAHPGDALOX15
SCHEMBL11694686 0.87 EPHX1 (0.51) ALDH1A1HSD17B10LMNAKMT2AMEN1
SCHEMBL11795382 0.81 ALDH1A1 (0.43) ALDH1A1HSD17B10LMNAHPGDALOX15
SCHEMBL11795388 0.81 ALDH1A1 (0.43) ALDH1A1HSD17B10LMNAHPGDALOX15
Thiophanate SCHEMBL29398343 0.80 ALDH1A1 (0.70) ALDH1A1HSD17B10LMNAHPGDALOX15
Thiophanate SCHEMBL20842 0.80 ALDH1A1 (0.70) ALDH1A1HSD17B10LMNAHPGDALOX15
Thiophanate SCHEMBL7449541 0.78 ALDH1A1 (0.68) ALDH1A1HSD17B10LMNAHPGDALOX15
SCHEMBL11695730 0.77 ALDH1A1 (0.61) ALDH1A1HSD17B10LMNAHPGDALOX15
SCHEMBL11692198 0.77 ALDH1A1 (0.61) ALDH1A1HSD17B10LMNAHPGDALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4029813-A Fungicidal compositions containing bisthioureido-benzenes and methods for use thereof NIPPON SODA COMPANY LIMITED (JA) 1977-06-14 US claimed
US-4020095-A FUNGICIDES NIPPON SODA COMPANY LIMITED (JA) 1977-04-26 US claimed
US-3958008-A THIOALLAPHANATE COMPOUNDS NIPPON SODA COMPANY LIMITED (JA) 1976-05-18 US claimed
US-3958008-A THIOALLAPHANATE COMPOUNDS NIPPON SODA COMPANY LIMITED (JA) 1976-05-18 US disclosed