SCHEMBL11796355

SCHEMBL11796355

CCCC(C(=O)O)(c1cccc(O)c1[N+](=O)[O-])c1cccc(O)c1[N+](=O)[O-]

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 1/20 0.44
ALDH1A1 P00352 4/20 0.34
TDP1 Q9NUW8 2/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
NPSR1 Q6W5P4 2/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TRPM8 Q7Z2W7 1/20 0.32
HTT P42858 2/20 0.32
BID P55957 3/20 0.31
MCL1 Q07820 3/20 0.31
BCL2L1 Q07817 2/20 0.31
BAK1 Q16611 2/20 0.31
KAT8 Q9H7Z6 2/20 0.31
PPARG P37231 1/20 0.31
PPARA Q07869 1/20 0.31
EP300 Q09472 1/20 0.31
KAT2A Q92830 1/20 0.31
KAT2B Q92831 1/20 0.31
KAT5 Q92993 1/20 0.31
SAE1 Q9UBE0 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11796359 0.81 GPR35 (0.49) GPR35ALDH1A1TDP1L3MBTL1NPSR1
SCHEMBL3793995 0.79 ALDH1A1 (0.44) ALDH1A1TDP1L3MBTL1NPSR1SMN1; SMN2
SCHEMBL31483969 0.75 GPR35 (0.50) GPR35ALDH1A1TDP1L3MBTL1NPSR1
SCHEMBL2792217 0.71 GPR35 (0.56) GPR35ALDH1A1TDP1TSHRMEN1
SCHEMBL4908577 0.70 ALDH1A1 (0.41) ALDH1A1TDP1L3MBTL1HTTBID
SCHEMBL25383024 0.69 ESR1 (0.44) GPR35ALDH1A1L3MBTL1SMN1; SMN2HTT
SCHEMBL28892811 0.69 CYP2C19 (0.39) ALDH1A1TDP1L3MBTL1NPSR1SMN1; SMN2
SCHEMBL28762464 0.69 ACP3 (0.43) ALDH1A1TDP1PPARGPPARATSHR
SCHEMBL70533 0.69 GPR35 (0.75) GPR35ALDH1A1TDP1TSHR
SCHEMBL31395812 0.69 GPR35 (0.58) GPR35ALDH1A1TDP1HTTTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3931029-A CYCLOHEXENE CARBOXYLIC ACIDS OR AMIDES BASF WYANDOTTE CORPORATION (US) 1976-01-06 US disclosed