Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 11/20 | 0.57 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5696373 | 1.00 | KIF11 (0.57) | KIF11ACEIDO1KLKB1ALDH1A1 | |
| SCHEMBL5695657 | 0.87 | KIF11 (0.59) | KIF11ACEKLKB1SLC7A5GLO1 | |
| SCHEMBL1158095 | 0.87 | KIF11 (0.56) | KIF11ACEALDH1A1 | |
| SCHEMBL1158094 | 0.87 | KIF11 (0.56) | KIF11ACEALDH1A1 | |
| SCHEMBL919742 | 0.87 | KIF11 (0.56) | KIF11ACEALDH1A1 | |
| Hydrochloric Acid SCHEMBL7323852 | 0.85 | KIF11 (0.55) | KIF11ACEIDO1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27713539 | 0.85 | KIF11 (0.55) | KIF11ACEIDO1ALDH1A1 | |
| SCHEMBL24434185 | 0.85 | SLC7A5 (0.61) | KIF11KLKB1SLC7A5GLO1 | |
| SCHEMBL22887318 | 0.84 | KIF11 (0.49) | KIF11KLKB1SLC7A5 | |
| SCHEMBL5695688 | 0.84 | SLC6A4 (0.47) | KIF11ACEKLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3975365-A | Inhibitory octapeptides angiotensin II | G. D. SEARLE & CO. (US) | 1976-08-17 | — | — | US | disclosed |