SCHEMBL1158095

SCHEMBL1158095

Cc1ccc(CSC[C@H](N)C(=O)O)cc1

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
KIF11 P52732 9/20 0.56
ACE P12821 1/20 0.52
PPARG P37231 1/20 0.48
PPARA Q07869 1/20 0.48
LMNA P02545 1/20 0.44
ALDH1A1 P00352 2/20 0.44
GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1158094 1.00 KIF11 (0.56) KIF11ACEPPARGPPARALMNA
SCHEMBL919742 1.00 KIF11 (0.56) KIF11ACEPPARGPPARALMNA
Hydrochloric Acid SCHEMBL27713539 0.98 KIF11 (0.55) KIF11ACEPPARGPPARALMNA
Hydrochloric Acid SCHEMBL7323852 0.98 KIF11 (0.55) KIF11ACEPPARGPPARALMNA
SCHEMBL5696373 0.87 KIF11 (0.57) KIF11ACEALDH1A1
SCHEMBL7319459 0.87 IDO1 (0.47) KIF11ACEPPARGPPARALMNA
SCHEMBL11796402 0.87 KIF11 (0.57) KIF11ACEALDH1A1
SCHEMBL24434185 0.85 SLC7A5 (0.61) KIF11
Benzylcysteine SCHEMBL515922 0.84 ALPI (0.58) KIF11ACE
Benzylcysteine SCHEMBL1109643 0.84 ALPI (0.58) KIF11ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250353814-A1 NON-PEPTIDIC CELL-PENETRATING MOTIFS OHIO STATE INNOVATION FOUNDATION (US) 2025-11-20 US claimed
US-12404236-B2 Non-peptidic cell-penetrating motifs OHIO STATE INNOVATION FOUNDATION (US) 2025-09-02 US claimed
US-12329799-B2 Peptidyl inhibitors of calcineurin-NFAT interaction OHIO STATE INNOVATION FOUNDATION (US) 2025-06-17 US claimed
CN-116120936-B Etching liquid medicine and preparation method and application thereof 上海天承化学有限公司 2024-06-25 CN claimed
US-20240101509-A1 NON-PEPTIDIC CELL-PENETRATING MOTIFS OHIO STATE INNOVATION FOUNDATION 2024-03-28 US claimed
CN-117567639-A Polypeptide conjugates for intracellular delivery of binding peptides 俄亥俄州国家创新基金会 2024-02-20 CN claimed
US-20240033318-A1 PEPTIDYL INHIBITORS OF CALCINEURIN-NFAT INTERACTION OHIO STATE INNOVATION FOUNDATION 2024-02-01 US claimed
US-11814341-B2 Non-peptidic cell-penetrating motifs OHIO STATE INNOVATION FOUNDATION (US) 2023-11-14 US claimed
US-20230212235-A1 LOOPED PROTEINS COMPRISING CELL PENETRATING PEPTIDES NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2023-07-06 US claimed
CN-116120936-A Etching liquid medicine and preparation method and application thereof 上海天承化学有限公司 2023-05-16 CN claimed
EP-4085064-A1 LOOPED PROTEINS COMPRISING CELL PENETRATING PEPTIDES Ohio State Innovation Foundation (US) 2022-11-09 EP claimed
CN-115135665-A Cyclic proteins comprising cell penetrating peptides 俄亥俄州国家创新基金会 2022-09-30 CN claimed
WO-2022109058-A1 NUCLEASES COMPRISING CELL PENETRATING PEPTIDE SEQUENCES ENTRADA THERAPEUTICS, INC. (US) 2022-05-27 WO claimed
WO-2021138397-A1 LOOPED PROTEINS COMPRISING CELL PENETRATING PEPTIDES OHIO STATE INNOVATION FOUNDATION (US) 2021-07-08 WO claimed
EP-3787671-A1 NON-PEPTIDIC CELL-PENETRATING MOTIFS Ohio State Innovation Foundation (US) 2021-03-10 EP claimed
US-4960881-A REACTING AMINO ACID WITH ALPHA-CHLORINATED CARBONATE IN SOLVENT IN PRESENCE OF ACID SCAVENGER SOCIETE NATIONALE DES POUDRES ET EXPLOSIFS (FR) 1990-10-02 US claimed
US-3976781-A SULFUR CONTAINING AMINES L'OREAL (FR) 1976-08-24 US claimed
US-20260125426-A1 CYCLIC CELL-PENETRATING PEPTIDES AND USES THEREOF OHIO STATE INNOVATION FOUNDATION (US) 2026-05-07 US disclosed
EP-0254032-A2 Neutral metalloendopeptidase inhibitors in the treatment of hypertension SCHERING CORPORATION (US) 1988-01-27 EP disclosed
US-3975365-A Inhibitory octapeptides angiotensin II G. D. SEARLE & CO. (US) 1976-08-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12404236-B2 Non-peptidic cell-penetrating motifs TIMM50, TIMM10, PITRM1 KIF11 3188/4885ACE 4841/4885PPARG 2558/4885
US-20240101509-A1 NON-PEPTIDIC CELL-PENETRATING MOTIFS TIMM50, TIMM10, PITRM1 KIF11 3188/4885ACE 4841/4885PPARG 2558/4885
US-20250353814-A1 NON-PEPTIDIC CELL-PENETRATING MOTIFS TIMM50, TIMM10, PITRM1 KIF11 3188/4885ACE 4841/4885PPARG 2558/4885
US-20230212235-A1 LOOPED PROTEINS COMPRISING CELL PENETRATING PEPTIDES LNPEP, SPPL2B, CNBP KIF11 3139/4885ACE 3693/4885PPARG 4682/4885
US-20260125426-A1 CYCLIC CELL-PENETRATING PEPTIDES AND USES THEREOF SLC7A1, TAP1, SLC7A5 KIF11 4673/4885ACE 3598/4885PPARG 4308/4885
US-11814341-B2 Non-peptidic cell-penetrating motifs TIMM50, TIMM10, PITRM1 KIF11 3188/4885ACE 4841/4885PPARG 2558/4885
US-12329799-B2 Peptidyl inhibitors of calcineurin-NFAT interaction CHP1, NFATC1, PPP3R1 KIF11 4622/4885ACE 2182/4885PPARG 4701/4885
US-20240033318-A1 PEPTIDYL INHIBITORS OF CALCINEURIN-NFAT INTERACTION CHP1, NFATC1, PPP3R1 KIF11 4622/4885ACE 2182/4885PPARG 4701/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.