Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | BMP1 | P13497 | 3/20 | 0.49 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11793418 | 0.98 | MAPK1 (0.55) | MAPK1TBXA2RALDH1A1BMP1MEP1B | |
| SCHEMBL11796476 | 0.93 | MAPK1 (0.53) | MAPK1TBXA2RALDH1A1BMP1MEP1B | |
| SCHEMBL11796389 | 0.92 | ALDH1A1 (0.54) | MAPK1TBXA2RALDH1A1HTTCA12 | |
| SCHEMBL11793539 | 0.88 | MAPK1 (0.55) | MAPK1TBXA2RALDH1A1BMP1HTT | |
| SCHEMBL579010 | 0.81 | TDP1 (0.64) | MAPK1HTTCA12CA9CA1 | |
| SCHEMBL29173159 | 0.81 | TDP1 (0.64) | MAPK1HTTCA12CA9CA1 | |
| SCHEMBL8349234 | 0.81 | TDP1 (0.64) | MAPK1HTTCA12CA9CA1 | |
| SCHEMBL18763131 | 0.81 | TDP1 (0.64) | MAPK1HTTCA12CA9CA1 | |
| SCHEMBL13589964 | 0.79 | KEAP1 (0.55) | ALDH1A1MEP1BCA12CA9CA1 | |
| SCHEMBL1278659 | 0.79 | TDP1 (0.67) | MAPK1HTTCA12CA9CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3992306-A | BIS-SULFONAMIDO-BIS-CARBOXYLIC ACID | HOECHST AKTIENGESELLSCHAFT (DT) | 1976-11-16 | — | — | US | disclosed |