Stearic Acid

Stearic Acid

SCHEMBL1179754

CCCCCCCCCCCCCCCCCC(=O)O.NC(N)=O

nearest known ligand 0.85

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.85
PPARG P37231 7/20 0.85
PPARD Q03181 7/20 0.85
PPARA Q07869 7/20 0.85
HDAC11 Q96DB2 5/20 0.85
TSHR P16473 4/20 0.85
PTPN1 P18031 3/20 0.85
FABP4 P15090 3/20 0.85
ALDH1A1 P00352 2/20 0.85
TLR2 O60603 2/20 0.85
TDP1 Q9NUW8 2/20 0.85
KMT2A Q03164 2/20 0.85
ALOX15 P16050 2/20 0.85
HSD17B10 Q99714 2/20 0.85
SLC22A6 Q4U2R8 1/20 0.85
SLC22A8 Q8TCC7 1/20 0.85
MEN1 O00255 1/20 0.85
ESR1 P03372 1/20 0.85
PDE4A P27815 1/20 0.85
PDE3A Q14432 1/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Heptanoate SCHEMBL1180258 1.00 GPR84 (0.85) GPR84PPARGPPARDPPARAHDAC11
Decanoic Acid SCHEMBL825467 1.00 GPR84 (0.85) GPR84PPARGPPARDPPARAHDAC11
Pentadecanoic Acid SCHEMBL825468 1.00 GPR84 (0.85) GPR84PPARGPPARDPPARAHDAC11
Dodecanoate SCHEMBL6130627 1.00 GPR84 (0.85) GPR84PPARGPPARDPPARAHDAC11
Palmitic Acid SCHEMBL9441466 1.00 GPR84 (0.85) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL27614355 1.00 GPR84 (0.85) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL28124674 0.95 GPR84 (0.77) GPR84PPARGPPARDPPARAHDAC11
Stearic Acid SCHEMBL9164221 0.95 GPR84 (0.85) GPR84PPARGPPARDPPARAHDAC11
Dodecanoate SCHEMBL27836399 0.95 GPR84 (0.85) GPR84PPARGPPARDPPARAHDAC11
Behenic Acid SCHEMBL26611758 0.95 GPR84 (0.85) GPR84PPARGPPARDPPARAHDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118716489-A Formula grass feed and preparation method and application thereof 内蒙古自治区农牧业科学院 2024-10-01 CN claimed
CN-106589957-A Silicon rubber foam material with high porosity and stable cellular structure and preparation method of silicon rubber foam material 青岛科技大学 2017-04-26 CN claimed
CN-118716489-A Formula grass feed and preparation method and application thereof 内蒙古自治区农牧业科学院 2024-10-01 CN disclosed
CN-117740721-A Method for detecting non-protein nitrogen content in feed raw material 江苏傲农生物科技有限公司 2024-03-22 CN disclosed
CN-113428993-A Compound potassium fulvate boiler scale remover and recycling method 上海臻衍生物科技有限公司 2021-09-24 CN disclosed
EP-2302620-B1 IMPACT AND SOUND ABSORBING MATERIAL AND SOUND ABSORBING STRUCTURE NAGOYA OILCHEMICAL (JP) 2021-03-03 EP disclosed
EP-2236286-B1 SOUND ABSORBING SKIN MATERIAL AND SOUND ABSORBING MATERIAL UTILIZING THE SAME NAGOYA OILCHEMICAL (JP) 2020-12-23 EP disclosed
CN-102363016-B A kind of Chinese medicine composite dripping core pills and preparation method thereof 无锡济民可信山禾药业股份有限公司 2017-12-05 CN disclosed
CN-106589957-A Silicon rubber foam material with high porosity and stable cellular structure and preparation method of silicon rubber foam material 青岛科技大学 2017-04-26 CN disclosed
CN-101970201-B Mold release sheet and molded articles NAGOYA OILCHEMICAL 2013-11-06 CN disclosed
CN-101945762-B Sound absorbing skin material and sound absorbing material utilizing the same NAGOYA OILCHEMICAL 2013-11-06 CN disclosed
CN-1205024-C Interior material NAGOYA OIL CHEMICAL CO LTD (JP) 2005-06-08 CN disclosed
CN-1474746-A Interior material 名古屋油化株式会社 2004-02-11 CN disclosed
CN-1408748-A Plastic foaming and and its preparing method YONGXIN CHEMICAL PLANT YIXING (CN) 2003-04-09 CN disclosed
EP-0984031-A1 MOLDING MATERIAL, INNER MATERIAL USING THE SAME, AND METHOD FOR PRODUCING THE SAME Nagoya Oilchemical Co., Ltd. (JP) 2000-03-08 EP disclosed
EP-0399554-B1 Foamable silicone composition, silicone sponge, and silicone sponge roll SHINETSU CHEMICAL CO (JP) 1995-03-08 EP disclosed
US-5288619-A Margarine KRAFT GENERAL FOODS, INC. (US) 1994-02-22 US disclosed
US-5120385-A Blend with filler, azodicarbonamide foaming agent and diacyl peroxide SHIN ETSU CHEMICAL COMPANY, LTD. (JP) 1992-06-09 US disclosed
WO-1991008676-A1 LOW-SATURATE EDIBLE OILS AND TRANSESTERIFICATION METHODS FOR PRODUCTION THEREOF KRAFT GENERAL FOODS, INC. (US) 1991-06-27 WO disclosed
EP-0399554-A2 Foamable silicone composition, silicone sponge, and silicone sponge roll SHIN-ETSU CHEMICAL CO., LTD. (JP) 1990-11-28 EP disclosed