Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.77 |
| ▸ | PPARG | P37231 | 7/20 | 0.77 |
| ▸ | PPARD | Q03181 | 7/20 | 0.77 |
| ▸ | PPARA | Q07869 | 7/20 | 0.77 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.77 |
| ▸ | TSHR | P16473 | 4/20 | 0.77 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.77 |
| ▸ | FABP4 | P15090 | 3/20 | 0.77 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.77 |
| ▸ | TLR2 | O60603 | 2/20 | 0.77 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.77 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.77 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.77 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.77 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.77 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.77 |
| ▸ | MEN1 | O00255 | 1/20 | 0.77 |
| ▸ | ESR1 | P03372 | 1/20 | 0.77 |
| ▸ | PDE4A | P27815 | 1/20 | 0.77 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Palmitic Acid SCHEMBL9441466 | 0.95 | GPR84 (0.85) | GPR84PPARGPPARDPPARAHDAC11 | |
| Decanoic Acid SCHEMBL825467 | 0.95 | GPR84 (0.85) | GPR84PPARGPPARDPPARAHDAC11 | |
| Heptanoate SCHEMBL1180258 | 0.95 | GPR84 (0.85) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL27614355 | 0.95 | GPR84 (0.85) | GPR84PPARGPPARDPPARAHDAC11 | |
| Dodecanoate SCHEMBL6130627 | 0.95 | GPR84 (0.85) | GPR84PPARGPPARDPPARAHDAC11 | |
| Pentadecanoic Acid SCHEMBL825468 | 0.95 | GPR84 (0.85) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL1179754 | 0.95 | GPR84 (0.85) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL7147503 | 0.93 | GPR84 (0.90) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL7456277 | 0.93 | GPR84 (0.90) | GPR84PPARGPPARDPPARAHDAC11 | |
| Stearic Acid SCHEMBL9164221 | 0.91 | GPR84 (0.85) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106459523-B | The manufacturing method of resin combination, cross-linking agent and cross-linking agent | 住友化学株式会社 | 2019-11-19 | — | — | CN | disclosed |
| CN-109642086-A | resin composition and use thereof | 住友化学株式会社 | 2019-04-16 | — | — | CN | disclosed |
| CN-109312017-A | Polymer, molded article, foam, resin composition, and method for producing polymer | 住友化学株式会社 | 2019-02-05 | — | — | CN | disclosed |
| CN-109311270-A | Laminate, building material, building, and heat-insulating container | 住友化学株式会社 | 2019-02-05 | — | — | CN | disclosed |
| CN-106459523-A | Resin composition, cross-linked product, and method for manufacturing cross-linked product | 住友化学株式会社 | 2017-02-22 | — | — | CN | disclosed |