Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 8/20 | 0.62 |
| ▸ | PGR | P06401 | 8/20 | 0.62 |
| ▸ | USP2 | O75604 | 7/20 | 0.62 |
| ▸ | HIF1A | Q16665 | 6/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.62 |
| ▸ | LMNA | P02545 | 6/20 | 0.62 |
| ▸ | CNR1 | P21554 | 4/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.57 |
| ▸ | AR | P10275 | 1/20 | 0.57 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.57 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11798350 | 1.00 | NR3C1 (0.62) | NR3C1PGRUSP2HIF1ACYP3A4 | |
| SCHEMBL11788733 | 0.94 | NR3C1 (0.70) | NR3C1PGRUSP2HIF1ACYP3A4 | |
| SCHEMBL11788721 | 0.94 | NR3C1 (0.70) | NR3C1PGRUSP2HIF1ACYP3A4 | |
| SCHEMBL11794144 | 0.92 | NR3C1 (0.64) | NR3C1PGRUSP2HIF1ACYP3A4 | |
| SCHEMBL11794137 | 0.92 | NR3C1 (0.64) | NR3C1PGRUSP2HIF1ACYP3A4 | |
| SCHEMBL11795449 | 0.92 | PGR (0.54) | NR3C1PGRUSP2HIF1ACYP3A4 | |
| SCHEMBL11795442 | 0.92 | PGR (0.54) | NR3C1PGRUSP2HIF1ACYP3A4 | |
| SCHEMBL11791454 | 0.90 | NR3C1 (0.58) | NR3C1PGRUSP2HIF1ACYP3A4 | |
| SCHEMBL11791396 | 0.90 | NR3C1 (0.58) | NR3C1PGRUSP2HIF1ACYP3A4 | |
| SCHEMBL11792650 | 0.89 | USP2 (0.65) | NR3C1PGRUSP2HIF1ACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3933799-A | HORMONES | GLAXO LABORATORIES LIMITED (EN) | 1976-01-20 | — | — | US | disclosed |