SCHEMBL11798519

SCHEMBL11798519

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](N)C(C)C)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ ACE P12821 11/20 0.58
▸ MME P08473 4/20 0.58
▸ CPA1 P15085 4/20 0.58
▸ ACE2 Q9BYF1 4/20 0.58
▸ LNPEP Q9UIQ6 6/20 0.56
▸ ANPEP P15144 5/20 0.56
▸ CTSD P07339 1/20 0.49
▸ OPRM1 P35372 1/20 0.47
▸ OPRD1 P41143 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17274195 1.00 ACE (0.58) ACEMMECPA1ACE2LNPEP
SCHEMBL18699897 1.00 ACE (0.58) ACEMMECPA1ACE2LNPEP
SCHEMBL11799067 1.00 ACE (0.58) ACEMMECPA1ACE2LNPEP
SCHEMBL29352065 0.91 ACE (0.58) ACEMMECPA1ACE2LNPEP
SCHEMBL29351159 0.91 ACE (0.60) ACEMMECPA1ACE2LNPEP
SCHEMBL30052882 0.91 CTSD (0.58) ACEMMECPA1ACE2LNPEP
SCHEMBL29386631 0.91 MME (0.50) ACEMMECPA1ACE2LNPEP
SCHEMBL29350566 0.91 MME (0.50) ACEMMECPA1ACE2LNPEP
SCHEMBL29822653 0.90 ACE (0.59) ACEMMECPA1ACE2OPRM1
SCHEMBL31318683 0.88 ACE (0.57) ACEMMECPA1ACE2LNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106456698-B Synthesis of beta-arrestin effectors 特维娜有限公司 2022-05-17 — — CN claimed
US-12433932-B2 Ang (1-7) derivative oligopeptides for the treatment of pain ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2025-10-07 — — US disclosed
EP-4371556-A1 ANGIOTENSIN(1-7) PHARMACEUTICAL COMPOSITIONS FOR INHALATION Explicat Pharma GmbH (DE) 2024-05-22 — — EP disclosed
CN-117120417-A Methods and agents for stimulating mitochondrial turnover to treat diseases 容量生物公司 2023-11-24 — — CN disclosed
US-20230226140-A1 ANG (1-7) DERVIATIVE OLIGOPEPTIDES FOR THE TREATMENT OF PAIN ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA 2023-07-20 — — US disclosed
EP-3565575-B1 ANG (1-7) DERIVATIVE OLIGOPEPTIDES FOR THE TREATMENT OF PAIN UNIV ARIZONA (US) 2023-03-08 — — EP disclosed
CN-106456698-B Synthesis of beta-arrestin effectors 特维娜有限公司 2022-05-17 — — CN disclosed
US-20180016301-A1 Synthesis of Beta-Arrestin Effectors FOREST LABORATORIES HOLDINGS LIMITED (BM) 2018-01-18 — — US disclosed
US-9611293-B2 Synthesis of beta-arrestin effectors TREVENA, INC. (US) 2017-04-04 — — US disclosed
US-20150329593-A1 Synthesis of Beta-Arrestin Effectors FOREST LABORATORIES HOLDINGS LIMITED (BM) 2015-11-19 — — US disclosed
US-3975365-A Inhibitory octapeptides angiotensin II G. D. SEARLE & CO. (US) 1976-08-17 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180016301-A1 Synthesis of Beta-Arrestin Effectors ARRB1, ADRB1, ADRB3 ACE 1568/4885MME 2361/4885CPA1 3030/4885
US-20150329593-A1 Synthesis of Beta-Arrestin Effectors ARRB1, ADRB1, ADRB3 ACE 1568/4885MME 2361/4885CPA1 3030/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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