SCHEMBL11799145

SCHEMBL11799145

BrOc1c(Br)c(Br)c(Br)c(Br)c1-c1c(Br)c(Br)c(Br)c(Br)c1OBr

nearest known ligand 0.36

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10522596 0.75 MAPK1 (0.36) TSHR
SCHEMBL7588912 0.67 CA1 (0.56)
SCHEMBL28689537 0.67
SCHEMBL192021 0.64 TSHR (0.44) TSHR
SCHEMBL11881165 0.64 TSHR (0.44) TSHR
SCHEMBL437021 0.62 PTPN1 (0.35) TSHR
SCHEMBL10338803 0.62 PTPN1 (0.35) TSHR
SCHEMBL10656649 0.60 TSHR (0.41) TSHR
Water SCHEMBL1127581 0.60 TSHR (0.41) TSHR
SCHEMBL211401 0.60 PTPN1 (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-3989531-A POLYSTYRENE GENERAL ELECTRIC COMPANY (US) 1976-11-02 US disclosed